Antônio Flávia Ignácio, Bo Kari, Ferriani Rui Alberto, de Sá Marcos Felipe Silva, de Sá Rosa e Silva Ana Carolina Japur, Ferreira Cristine Homsi Jorge
Department of Rehabilitation and Functional Performance, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Av. Bandeirantes, 3900 Monte Alegre, 14049-900, Ribeirão Preto, SP, Brazil.
Int Urogynecol J. 2013 Oct;24(10):1709-14. doi: 10.1007/s00192-013-2095-x. Epub 2013 Apr 11.
Hyperandrogenism in women with polycystic ovary syndrome (PCOS) could increase muscle mass and thereby pelvic floor muscle (PFM) strength, reducing the risk of urinary incontinence (UI). The aim of the present study was to assess PFM strength and UI among hyperandrogenic women with PCOS and a control group for comparison.
This is an observational, cross-sectional, case-control study. Seventy-nine women, aged 18 to 40 years with a mean body mass index (BMI) of 23.4 kg/cm(2) were recruited at the University Hospital: PCOS (n = 36) and control group for comparison (n = 43). All PCOS women had clinical and/or laboratory hyperandrogenism (> 80 ng/dL) and control women had regular menstrual cycles. PFM strength was assessed by vaginal manometry. The International Consultation on Incontinence Questionnaire of Urinary Incontinence Short Form (ICIQ-UI SF) was used to assess UI. Descriptive analysis, analysis of variance (ANOVA) and Fisher's exact test were used for statistical analyses.
There was no statistically significant difference in mean PFM strength between the PCOS and the control group: 2.7 cm H₂O (95% CI -6.2-11.6) p = 0.55. The prevalence of UI was 18.6% in the control group compared with 0% in the PCOS group p < 0.01.
Women with PCOS showed absence of UI, but PFM strength did not differ from the control group.
多囊卵巢综合征（PCOS）女性的高雄激素血症可能会增加肌肉量，从而增强盆底肌肉（PFM）力量，降低尿失禁（UI）风险。本研究旨在评估高雄激素血症的PCOS女性与对照组的PFM力量及尿失禁情况，以作比较。
这是一项观察性、横断面病例对照研究。在大学医院招募了79名年龄在18至40岁之间、平均体重指数（BMI）为23.4 kg/cm²的女性：PCOS组（n = 36）和对照组（n = 43）用于比较。所有PCOS女性均有临床和/或实验室高雄激素血症（> 80 ng/dL），对照组女性月经周期正常。通过阴道测压评估PFM力量。使用国际尿失禁咨询委员会尿失禁简表问卷（ICIQ-UI SF）评估尿失禁情况。采用描述性分析、方差分析（ANOVA）和Fisher精确检验进行统计分析。
PCOS组和对照组的平均PFM力量无统计学显著差异：2.7 cm H₂O（95%可信区间 -6.2 - 11.6），p = 0.55。对照组尿失禁患病率为18.6%，而PCOS组为0%，p < 0.01。
PCOS女性未出现尿失禁情况，但PFM力量与对照组无差异。
