Schroeder C E, Tenke C E, Givre S J, Arezzo J C, Vaughan H G
Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461.
Brain Res. 1990 May 7;515(1-2):326-30. doi: 10.1016/0006-8993(90)90617-k.
We investigated the laminar profile of visually evoked paroxysmal discharge following bicuculline administration in area 17 of the alert macaque. Paroxysmal discharge was focussed in lamina 3, with lesser concomitants in infragranular laminae. There were no marked effects on the flash-evoked laminar activation sequence. The neocortex of the alert macaque studied with the present techniques may provide a model for evaluating basic mechanisms of epilepsy, and for linking these to the macroscopic phenomena seen in humans.
我们研究了在警觉猕猴的17区注射荷包牡丹碱后视觉诱发阵发性放电的分层分布情况。阵发性放电集中在第3层，颗粒下层的放电较少。对闪光诱发的分层激活序列没有明显影响。用本技术研究的警觉猕猴的新皮层可能为评估癫痫的基本机制以及将这些机制与人类所见的宏观现象联系起来提供一个模型。
