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用于眼科兆赫兹光学相干断层扫描中散斑减少和提高采集效率的联合孔径检测

Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT.

作者信息

Klein Thomas, André Raphael, Wieser Wolfgang, Pfeiffer Tom, Huber Robert

机构信息

Lehrstuhl für BioMolekulare Optik, Fakultät für Physik, Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538 Munich, Germany.

出版信息

Biomed Opt Express. 2013 Apr 1;4(4):619-34. doi: 10.1364/BOE.4.000619. Epub 2013 Mar 28.

DOI:10.1364/BOE.4.000619
PMID:23577296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3617723/
Abstract

Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power on the sample. Additionally, JA-OCT provides angular scattering information about the sample in a single acquisition, so the OCT imaging speed is not reduced. Thus, JA-OCT is especially suitable for ultra high speed in-vivo imaging. JA-OCT is compared to other angle-resolved techniques, and the relation between joint aperture imaging, adaptive optics, coherent and incoherent compounding is discussed. We present angle-resolved imaging of the human retina at an axial scan rate of 1.68 MHz, and demonstrate the benefits of JA-OCT: Speckle reduction, signal increase and suppression of specular and parasitic reflections. Moreover, in the future JA-OCT may allow for the reconstruction of the full Doppler vector and tissue discrimination by analysis of the angular scattering dependence.

摘要

联合孔径光学相干断层扫描（JA - OCT）是一种角度分辨OCT方法，其中来自一个有源通道的照明光由多个无源通道同时探测。JA - OCT在不增加样品上功率的情况下提高了OCT系统的采集效率和有效灵敏度。此外，JA - OCT在单次采集时就能提供关于样品的角散射信息，因此不会降低OCT成像速度。所以，JA - OCT特别适用于超高速体内成像。将JA - OCT与其他角度分辨技术进行了比较，并讨论了联合孔径成像、自适应光学、相干和非相干复合之间的关系。我们以1.68 MHz的轴向扫描速率展示了人视网膜的角度分辨成像，并证明了JA - OCT的优势：减少散斑、增加信号以及抑制镜面反射和寄生反射。此外，未来JA - OCT可能通过分析角散射依赖性实现全多普勒矢量的重建和组织鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/618bec26df06/boe-4-4-619-g007.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/72965cbb5691/boe-4-4-619-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/618bec26df06/boe-4-4-619-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/a0d02257096e/boe-4-4-619-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/c303e0672b7c/boe-4-4-619-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/83ae181c4208/boe-4-4-619-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/124879346ca2/boe-4-4-619-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/a7658937a166/boe-4-4-619-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ae6/3617723/618bec26df06/boe-4-4-619-g007.jpg

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本文引用的文献

1
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J Biomed Opt. 1999 Jan;4(1):95-105. doi: 10.1117/1.429925.
2
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J Biomed Opt. 1998 Oct;3(4):446-55. doi: 10.1117/1.429897.
3
Frequency domain multiplexing for speckle reduction in optical coherence tomography.频域复用在光学相干断层扫描中的散斑减少。
用于可视化组织微观结构方向性的计算多向光学相干断层扫描技术。
Biomed Opt Express. 2021 Jun 7;12(7):3851-3864. doi: 10.1364/BOE.426125. eCollection 2021 Jul 1.
4
Real-time noise reduction based on ground truth free deep learning for optical coherence tomography.基于无真实标签深度学习的光学相干断层扫描实时降噪
Biomed Opt Express. 2021 Mar 12;12(4):2027-2040. doi: 10.1364/BOE.419584. eCollection 2021 Apr 1.
5
A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head.一种用于视神经头光学相干断层扫描图像去噪的深度学习方法。
Sci Rep. 2019 Oct 8;9(1):14454. doi: 10.1038/s41598-019-51062-7.
6
Ultra low noise Fourier domain mode locked laser for high quality megahertz optical coherence tomography.用于高质量兆赫兹光学相干断层扫描的超低噪声傅里叶域锁模激光器。
Biomed Opt Express. 2018 Aug 7;9(9):4130-4148. doi: 10.1364/BOE.9.004130. eCollection 2018 Sep 1.
7
Multi-directional optical coherence tomography for retinal imaging.用于视网膜成像的多方向光学相干断层扫描技术
Biomed Opt Express. 2017 Nov 13;8(12):5560-5578. doi: 10.1364/BOE.8.005560. eCollection 2017 Dec 1.
8
Single pulse two photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate.具有兆赫兹像素速率的单脉冲双光子荧光寿命成像（SP-FLIM）。
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9
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Biomed Opt Express. 2017 Feb 21;8(3):1721-1730. doi: 10.1364/BOE.8.001721. eCollection 2017 Mar 1.
10
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J Biophotonics. 2011 Aug;4(7-8):552-8. doi: 10.1002/jbio.201000104. Epub 2010 Nov 12.