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[使用氮冷探头进行环形冷冻凝固后的临床结果]

[Clinical results following cyclo-cryocoagulation with a nitrogen cooled probe].

作者信息

Böhnke M, Sayar R B

机构信息

Universitäts-Augenklinik, Hamburg.

出版信息

Fortschr Ophthalmol. 1990;87(2):134-7.

PMID:2358267
Abstract

A new cryoprobe for cyclocryocoagulation was investigated in a clinical trial. A group of 15 patients was treated with one step coagulation at 120 degrees C; a control group of 15 patients was treated with a CO2-cooled cryoprobe using circular coagulation in the usual manner. Statistical evaluation showed a significant drop in IOP in both groups after cryocoagulation. There was no difference in the preoperative IOP values (42 +/- 13 vs. 42 +/- 9 mmHg, p = 0.850), but in the postoperative evaluations done 1-2 and 6-9 months postoperatively we found lower IOPs in the nitrogen treated groups (13 +/- 7 vs. 27 +/- 11, p less than 0.001, U-test; 14 +/- 8 vs 24 +/- 17 mmHg, p = 0.044). This new cryoprobe seems to be suitable for a one-step procedure, as it shows results superior to multiple applications with the CO2-cooled cryoprobe.

摘要

在一项临床试验中对一种用于睫状体冷凝术的新型冷冻探头进行了研究。一组15例患者采用120摄氏度一步凝固法进行治疗;另一组15例患者作为对照组,采用常规方式使用二氧化碳冷却冷冻探头进行环形凝固治疗。统计学评估显示,两组冷凝术后眼压均显著下降。术前眼压值无差异(42±13 vs. 42±9 mmHg,p = 0.850),但在术后1 - 2个月和6 - 9个月进行的评估中,我们发现氮气治疗组的眼压较低(13±7 vs. 27±11,p < 0.001,U检验;14±8 vs 24±17 mmHg,p = 0.044)。这种新型冷冻探头似乎适用于一步手术,因为其显示出的结果优于使用二氧化碳冷却冷冻探头的多次应用。

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