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[青光眼患者中使用探头温度为-70摄氏度和-82摄氏度的睫状体环冷凝术的结果]

[Results of cyclo-cryocoagulation of the ciliary body with probe temperatures of -70 degrees C and -82 degrees C in glaucoma].

作者信息

Otto P, Harnisch J P

机构信息

Augenarztpraxis Berlin.

出版信息

Ophthalmologe. 1993 Dec;90(6):588-93.

PMID:8124019
Abstract

Cryocoagulation of the ciliary body has few applications. Cryotherapy in our study was standardized: 8 applications, 4 mm posterior to the limbus, 55 s, 2.5-mm-diameter cryoprobe. The aim of this research was to optimize the method by comparing the side effects of the treatment and the results of 128 operations as seen at follow-up examinations. When an applicator at -70 degrees C had been used, 54% of 52 eyes showed an IOP < 21 mmHg 12 months after operation. In all cases and adjuvant therapy was necessary. The IOP in 73% of these eyes rose to 30 mmHg for short periods. It was necessary to reoperate in 39% of the whole group. When a cryoprobe at -82 degrees C had been used IOP was found to have normalized in 89% of 76 eyes. In this group 34% of cases needed no other therapy. The IOP in the treated eyes showed peaks up to 30 mmHg in 34%. We performed revision operations in 7.9%. It was only possible to normalize the IOP of hemorrhagic glaucoma and glaucoma connected with PEX by using -82 degrees C applicator. Examinations over 30 months after treatment show nearly the same results. Side effects of cryocoagulation of ciliary body were observed. Postoperative IOP peaks exceeding 55 mmHg were recorded in 10% of cases. These can be avoided by osmotic therapy. The anterior chamber was inflamed with exudation of fibrin in about 4% of patients treated with a -70 degrees C probe and 16% treated with one at -82 degrees C.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

睫状体冷冻术的应用较少。我们研究中的冷冻疗法是标准化的:8次应用,在角膜缘后4毫米处,持续55秒,使用直径2.5毫米的冷冻探头。本研究的目的是通过比较治疗的副作用以及随访检查中128例手术的结果来优化该方法。当使用-70℃的敷贴器时,52只眼中有54%在术后12个月眼压<21 mmHg。在所有病例中,辅助治疗是必要的。这些眼中73%的眼压在短时间内升至30 mmHg。整个组中有39%的患者需要再次手术。当使用-82℃的冷冻探头时,76只眼中有89%的眼压恢复正常。在该组中,34%的病例无需其他治疗。治疗眼的眼压在34%的患者中高达30 mmHg。我们进行了7.9%的翻修手术。只有使用-82℃的敷贴器才能使出血性青光眼和与假性剥脱相关的青光眼的眼压恢复正常。治疗后30个月以上的检查显示结果几乎相同。观察到了睫状体冷冻术的副作用。10%的病例记录到术后眼压峰值超过55 mmHg。这些可以通过渗透性治疗避免。在用-70℃探头治疗的患者中约4%以及用-82℃探头治疗的患者中16%出现前房炎症伴纤维蛋白渗出。(摘要截短至250字)

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