Departament de Bioquimica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, and CIBER Fisiopatologia de la Obesidad y Nutrición, Av Diagonal 643, 08028 Barcelona, Catalonia, Spain.
Cell Metab. 2013 May 7;17(5):638-43. doi: 10.1016/j.cmet.2013.02.020. Epub 2013 Apr 11.
If we could avoid the side effects associated with global sympathetic activation, activating brown adipose tissue to increase thermogenesis would be a safe way to lose weight. The discovery of adrenergic-independent brown fat activators opens the prospect of developing this alternative way to efficiently and safely induce negative energy balance.
如果我们能够避免与全身交感神经激活相关的副作用，那么激活棕色脂肪组织以增加产热将是一种安全的减肥方法。发现肾上腺素能非依赖性棕色脂肪激活剂为开发这种替代方法以有效和安全地诱导负能平衡提供了前景。
