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经口内置吻合器输送系统施行全胃切除术后的食管空肠重建。

Esophagojejunal reconstruction after total gastrectomy for gastric cancer using a transorally inserted anvil delivery system.

机构信息

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

出版信息

Ann Surg Oncol. 2013 Sep;20(9):2975-83. doi: 10.1245/s10434-013-2978-6. Epub 2013 Apr 16.

Abstract

INTRODUCTION

Total gastrectomy (TG) is commonly performed for the treatment of patients with gastric cancer. However, reconstruction of the esophagojejunal (EJ) anastomosis can be technically demanding, with reported anastomotic leak rates in the Western world still approaching 10-15%. We report our experience using the transoral anvil delivery system (OrVil™) for creation of the EJ anastomosis after TG.

METHODS

From 2007 to 2011, 48 consecutive patients with gastric cancer underwent open (n=31) or laparoscopic (n=17) TG. EJ reconstruction was performed with the transoral anvil deliver system (OrVil™) in an end-to-side fashion. Demographic, clinic, and perioperative data were obtained from a prospectively maintained database.

RESULTS

Of the 48 patients, 83% were male. Median age at resection was 64 years. Median body mass index was 27.1 kg/m2. Seventy-nine percent (n=38) of patients had at least one comorbidity. Fifteen patients (31%) had at least one perioperative complication. There was one perioperative death (2%) following a duodenal stump leak. There were four EJ leaks (8%) and two EJ stenoses (independent of leak; 4%). There was one EJ leak (6%) and one EJ stenosis (6%) following a case that was first attempted laparoscopically. There were no deaths as a consequence of an EJ leak.

CONCLUSIONS

The use of the transoral anvil delivery system during EJ reconstruction is a safe and effective option for reconstruction after open or laparoscopic TG with acceptable mortality and morbidity. The anastomotic leak rate appears to be comparable to that of other techniques.

摘要

介绍

全胃切除术(TG)常用于治疗胃癌患者。然而,食管空肠(EJ)吻合术的重建技术要求较高,据报道,在西方国家,吻合口漏的发生率仍接近 10-15%。我们报告使用经口吻合器输送系统(OrVil™)进行 TG 后 EJ 吻合术的经验。

方法

从 2007 年到 2011 年,48 例胃癌患者接受了开放性(n=31)或腹腔镜(n=17)TG。EJ 重建采用经口吻合器输送系统(OrVil™)进行端侧吻合。从一个前瞻性维护的数据库中获得了人口统计学、临床和围手术期数据。

结果

在 48 例患者中,83%为男性。中位年龄为 64 岁。中位体重指数为 27.1kg/m2。79%(n=38)的患者至少有一种合并症。15 例(31%)患者至少有一种围手术期并发症。1 例患者(2%)在十二指肠残端漏后出现围手术期死亡。发生 4 例 EJ 漏(8%)和 2 例 EJ 狭窄(独立于漏;4%)。首次尝试腹腔镜治疗的患者中有 1 例 EJ 漏(6%)和 1 例 EJ 狭窄(6%)。没有因 EJ 漏而导致死亡。

结论

在开放性或腹腔镜 TG 后,使用经口吻合器输送系统进行 EJ 重建是一种安全有效的选择,其死亡率和发病率可以接受。吻合口漏的发生率似乎与其他技术相当。

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