Wang Xu, Gu Xiaoming, Zhang Zhiliang, Qiu Fang, Zhang Keming
Department of Emergency, Hangzhou Normal University, Hangzhou, China.
Ulus Travma Acil Cerrahi Derg. 2012 Nov;18(6):483-9. doi: 10.5505/tjtes.2012.08522.
The Injury Severity Score (ISS) and the New Injury Severity Score (NISS) are widely used for anatomic severity assessments, but they do not display a linear relation to mortality. The mortality rates are significantly different between pairs of the Abbreviated Injury Scale (AIS) triplets that generate the same ISS/NISS total.
The Logarithm Injury Severity Score (LISS) is defined as a change in AIS values by raising each AIS severity score (1-6) by taking the natural logarithm to a power of 5.53 multiplied by 1.7987 and then adding the three most severe injuries (i.e. highest AIS), regardless of body region. LISS values were calculated for every patient in three large independent data sets: 3,784, 4,436, and 4,018 patients treated over a six-year period at Class A tertiary comprehensive hospitals in China. The power of LISS to predict morality was then compared with previously calculated NISS values for the same patients in each of the three data sets.
We found that LISS is more predictive of survival as well (Hangzhou: receiver operating characteristic (ROC): NISS=0.931, LISS=0.949, p=0.006; Similarly, Zhejiang and Shenyang: ROC NISS vs. LISS, p<0.05). Moreover, LISS provides a better fit throughout its entire range of predicting (Hosmer-Lemeshow statistic for Hangzhou NISS=15.76, p=0.027; LISS=13.79, p=0.055; Similarly, for Zhejiang and Shenyang).
LISS should be used as the standard summary measure of human trauma.
损伤严重度评分(ISS)和新损伤严重度评分(NISS)被广泛用于解剖学严重程度评估,但它们与死亡率并无线性关系。产生相同ISS/NISS总和的简略损伤量表(AIS)三联组之间的死亡率存在显著差异。
对数损伤严重度评分(LISS)的定义为,将每个AIS严重度评分(1 - 6)提升至以自然对数为底、5.53乘以1.7987的幂次方,然后加上最严重的三处损伤(即最高AIS评分),无论身体部位如何,从而得出AIS值的变化。在中国甲级三级综合医院六年期间治疗的三个大型独立数据集中,为每位患者计算LISS值。这三个数据集分别包含3784例、4436例和4018例患者。然后将LISS预测死亡率的能力与之前在这三个数据集中为相同患者计算的NISS值进行比较。
我们发现LISS对生存率的预测性也更强(杭州:受试者工作特征曲线(ROC):NISS = 0.931,LISS = 0.949,p = 0.006;同样,浙江和沈阳:ROC NISS与LISS比较,p < 0.05)。此外,LISS在其整个预测范围内拟合度更好(杭州NISS的Hosmer - Lemeshow统计量 = 15.76,p = 0.027;LISS = 13.79,p = 0.055;同样,浙江和沈阳)。
LISS应作为人类创伤的标准汇总测量指标。