布-加综合征妊娠结局——一家三级医疗中心的经验。
Pregnancy outcome in Budd Chiari Syndrome--a tertiary care centre experience.
机构信息
Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, PGIMER, Chandigarh, 160012, India.
出版信息
Arch Gynecol Obstet. 2013 Oct;288(4):949-52. doi: 10.1007/s00404-013-2834-8. Epub 2013 Apr 17.
BACKGROUND
Pregnancy management is a crucial issue in women with Budd-Chiari Syndrome (BCS) and there are no established guidelines on the management.
AIM
To report our experience of pregnancy outcome with BCS.
MATERIAL AND METHODS
We report outcome of 13 pregnancies in three women, with favourable outcome after the diagnosis of the condition and its treatment using intervention to bypass obstruction and anticoagulant therapy during pregnancy.
RESULTS
Three women had a total of 13 pregnancies; three after the diagnosis and decompressive treatment of the disease. Disease was diagnosed during index pregnancy in two women. Anticoagulation was given in all the three pregnancies (Robertson et al., Br J Haematol, 132:171-196, 2006). Pregnancies prior to diagnosis and treatment resulted in a live birth.
CONCLUSION
Pregnancy does not seem to be a contraindication in well treated and controlled BCS. Maternal outcome is good with close multidisciplinary surveillance. Foetal outcome, however, may still be poor due to underlying prothrombotic condition.
背景
妊娠管理是布加综合征（BCS）女性的一个关键问题，目前尚无关于该病管理的既定指南。
目的
报告我们在布加综合征患者妊娠结局方面的经验。
材料与方法
我们报告了三例女性共 13 例妊娠的结局，在诊断该病后通过介入治疗绕过梗阻，并在妊娠期间使用抗凝治疗，结果良好。
结果
三例女性共妊娠 13 次；其中 3 次在疾病诊断和减压治疗后。另外 2 例在本次妊娠中诊断出疾病。在所有 3 次妊娠中均给予抗凝治疗（Robertson 等人，《英国血液学杂志》，132：171-196，2006）。在诊断和治疗之前的妊娠均导致活产。
结论
在经过良好治疗和控制的布加综合征患者中，妊娠似乎不是禁忌症。通过密切的多学科监测，母婴结局良好。然而，由于潜在的血栓形成状态，胎儿结局仍可能较差。
Zotero 插件