Merz Waltraut M, Rüland Anna M, Hippe Valeria, Poetzsch Bernd, Meyer Carsten, Pollok Joerg M, Gembruch Ulrich, Trebicka Jonel
From the Department of Obstetrics and Prenatal Medicine (WMM, AMR, UG), University Bonn Medical School; Department of Internal Medicine I (VH, JT); Institute of Experimental Hematology and Transfusion Medicine (BP); Department of Radiology (CM); and Department of General (JMP), Visceral, Thoracic, and Vascular Surgery, University Bonn Medical School, Bonn, Germany.
Medicine (Baltimore). 2016 May;95(22):e3817. doi: 10.1097/MD.0000000000003817.
Due to its rarity, experience with pregnancy in Budd-Chiari syndrome (BCS) is limited. With the advent of new treatment modalities, transjugular intrahepatic portosystemic shunt in particular, numbers of affected women seeking pregnancy with BCS are expected to rise. Here, we use a case that ended lethal within 2 years after delivery to discuss the effect of pregnancy on BCS and vice versa, and to highlight the necessity of a multidisciplinary teamwork. Additionally, a risk classification is proposed which may serve as a framework for preconception counseling and assist in the establishment and evaluation of treatment algorithms; its criteria need to be defined and assessed for their applicability in further studies.
由于布加综合征(BCS)较为罕见,关于BCS患者妊娠的经验有限。随着新治疗方式的出现,尤其是经颈静脉肝内门体分流术,预计寻求妊娠的BCS女性患者数量将会增加。在此,我们通过一个产后2年内死亡的病例来探讨妊娠对BCS的影响以及BCS对妊娠的影响,强调多学科团队合作的必要性。此外,我们提出了一种风险分类方法,它可作为孕前咨询的框架,并有助于建立和评估治疗方案;其标准需要在进一步研究中加以定义和评估其适用性。