密歇根州底特律市肥胖成年患者严重流感结局的流行病学研究，2011 年。
Epidemiology of severe influenza outcomes among adult patients with obesity in Detroit, Michigan, 2011.
机构信息
Department of Pharmacy Practice, Wayne State University, Detroit, MI, USA.
出版信息
Influenza Other Respir Viruses. 2013 Nov;7(6):1004-7. doi: 10.1111/irv.12115. Epub 2013 Apr 18.
Abstract
We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when compared with non-obese individuals. Among admitted individuals, persons with obesity were more likely to require a lengthy hospital stay [OR=3·86 (95% CI 1·03, 14·42), P=0·045]. Five of the six deaths in study subjects occurred in persons with obesity.
摘要
我们进行了一项回顾性队列研究，以评估肥胖对流感疾病严重程度的影响。与非肥胖者相比，肥胖者更有可能表现出较低的肺部疾病症状[比值比（OR）=1.97，95%置信区间（CI）1.053.69，P=0.03]，更有可能被收住入院[OR=2.93，95% CI 1.505.71，P=0.002]。在被收住入院的人群中，肥胖者更有可能需要较长的住院时间[OR=3.86，95% CI 1.03~14.42，P=0.045]。研究对象中有 5 人死亡，其中 6 人发生在肥胖者中。
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