From the *Department of Pediatrics, Division of Infectious Diseases; †Department of Pathology and Laboratory Medicine, Children's and Women's Health Centre of British Columbia; and ‡British Columbia Center for Disease Control Public Health Microbiology and Reference Lab, Vancouver, BC, Canada.
Pediatr Infect Dis J. 2013 Sep;32(9):1030-2. doi: 10.1097/INF.0b013e318296b424.
Clostridium difficile is the most common cause of antibiotic-associated diarrhea, and it occasionally causes extraintestinal infections. We present a case of C. difficile-associated diarrhea that led to vertebral osteomyelitis associated with hardware. The osteomyelitis became symptomatic 2 years after the initial diarrheal event. C. difficile recovered from internal hardware sites cannot simply be regarded as a contaminant but should be treated.
艰难梭菌是最常见的抗生素相关性腹泻的病因，偶尔也会引起肠道外感染。我们报告 1 例艰难梭菌相关性腹泻导致与内固定相关的椎骨骨髓炎的病例。腹泻事件发生 2 年后，骨髓炎出现症状。从内部硬件部位分离出的艰难梭菌不应简单地视为污染物，而应予以治疗。
