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工作场所戒烟成功的预测因素:一项纵向研究。

Predictors of success for smoking cessation at the workplace: a longitudinal study.

机构信息

Clinic of Pneumology and Pulmonary Research, University Hospital Basel, Basel, Switzerland.

出版信息

Respiration. 2014;87(1):18-25. doi: 10.1159/000346646. Epub 2013 Apr 10.

Abstract

BACKGROUND

The effectiveness of worksite interventions to reduce smoking is debatable.

OBJECTIVES

A comprehensive smoking cessation intervention was implemented in a community of more than 17,000 employees at three different health care companies. The primary endpoint was abstinence at 24 months (self-reported and confirmed by exhaled carbon monoxide ≤ 6 parts per million). Predictors of long-term abstinence were analysed by multivariable regression analysis.

METHODS

The study was designed as an investigator-initiated and investigator-driven, open, multicentre, cohort study; 887 smokers were enrolled in the programme. The intervention included intensive individual counselling as well as nicotine replacement and/or bupropion according to individual preferences. Re-interventions for relapse were offered during the 24-month follow-up.

RESULTS

The abstinence rate was 37% at 24 months and did not differ among the various medication groups (p > 0.05 for all). Predictors of successful cessation were higher age (odds ratio, OR 1.47, 95% confidence interval, CI 1.08-2.00, p < 0.01), breathlessness on exertion (OR 2.26, 95% CI 1.1-4.9, p = 0.03), and a higher educational level (OR 1.81, 95% CI 1.06-3.09, p = 0.03). Higher Fagerström (OR 0.76, 95% CI 0.59-0.97, p < 0.01) and craving scores (OR 0.75, 95% CI 0.63-0.89, p < 0.01), chronic sputum production (OR 0.52, 95% CI 0.31-0.87, p = 0.01) and use of antidepressants (OR 0.54, 95% CI 0.32-0.91, p = 0.02) were associated with ongoing smoking.

CONCLUSION

A comprehensive smoking cessation intervention at the workplace achieves high, stable, long-term abstinence rates. Elderly, well-educated employees with breathlessness on exertion have higher odds of quitting smoking. In contrast, those with high physical dependency and more intense craving, and those reporting use of antidepressant medication or sputum production have poorer chances to quit.

摘要

背景

工作场所干预措施减少吸烟的效果存在争议。

目的

在三家不同的医疗保健公司的一个拥有超过 17000 名员工的社区中实施了一项综合性戒烟干预措施。主要终点是 24 个月时的戒烟率(自我报告并通过呼出的一氧化碳≤6ppm 确认)。通过多变量回归分析分析了长期戒烟的预测因素。

方法

该研究设计为研究者发起和驱动的、开放的、多中心、队列研究;887 名吸烟者参与了该项目。该干预措施包括强化个体咨询以及根据个人偏好使用尼古丁替代物和/或安非他酮。在 24 个月的随访期间提供复发性戒烟干预。

结果

24 个月时的戒烟率为 37%,且在各药物组之间无差异(所有组间 p>0.05)。成功戒烟的预测因素包括较高的年龄(优势比,OR 1.47,95%置信区间,CI 1.08-2.00,p<0.01)、运动时呼吸困难(OR 2.26,95%CI 1.1-4.9,p=0.03)和较高的教育水平(OR 1.81,95%CI 1.06-3.09,p=0.03)。较高的 Fagerström(OR 0.76,95%CI 0.59-0.97,p<0.01)和渴望评分(OR 0.75,95%CI 0.63-0.89,p<0.01)、慢性咳痰(OR 0.52,95%CI 0.31-0.87,p=0.01)和使用抗抑郁药(OR 0.54,95%CI 0.32-0.91,p=0.02)与持续吸烟有关。

结论

在工作场所实施全面的戒烟干预措施可实现高、稳定、长期的戒烟率。有呼吸困难的老年、受教育程度高的员工戒烟的几率更高。相比之下,那些身体依赖程度高、渴望程度高、报告使用抗抑郁药或咳痰的人戒烟的机会较差。

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