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戒烟成功率:心理准备起着关键作用,并与精神活性物质等其他因素相互作用。

Success rates in smoking cessation: Psychological preparation plays a critical role and interacts with other factors such as psychoactive substances.

作者信息

Joly Bertrand, Perriot Jean, d'Athis Philippe, Chazard Emmanuel, Brousse Georges, Quantin Catherine

机构信息

Biostatistics and Bioinformatics (DIM), University Hospital, Dijon, France; Bourgogne Franche-Comté University, Dijon, France.

Dispensaire Emile Roux, Centre d'Aide à I'Arrêt du Tabagisme (IRAAT), Centre de Lutte Anti-Tuberculeuse (CLAT), Clermont-Ferrand, France.

出版信息

PLoS One. 2017 Oct 11;12(10):e0184800. doi: 10.1371/journal.pone.0184800. eCollection 2017.

Abstract

INTRODUCTION

The aim of this study was to identify factors associated with the results of smoking cessation attempts.

METHODS

Data were collected in Clermont-Ferrand from a smoking cessation clinic between 1999 and 2009 (1,361 patients). Smoking cessation was considered a success when patients were abstinent 6 months after the beginning of cessation. Multivariate logistic regression was used to investigate the association between abstinence and different factors.

RESULTS

The significant factors were a history of depression (ORadjusted = 0.57, p = 0.003), state of depression at the initial consultation (ORa = 0.64, p = 0.005), other psychoactive substances (ORa = 0.52, p<0.0001), heart, lung and Ear-Nose-Throat diseases (ORa = 0.65, p = 0.005), age (ORa = 1.04, p<0.0001), the Richmond test (p<0.0001; when the patient's motivation went from insufficient to moderate, the frequency of abstinence was twice as high) and the Prochaska algorithm (p<0.0001; when the patient went from the 'pre-contemplation' to the 'contemplation' level, the frequency of success was four times higher). A high score in the Richmond test had a greater impact on success with increasing age (significant interaction: p = 0.01). In exclusive smokers, the contemplation level in the Prochaska algorithm was enough to obtain a satisfactory abstinence rate (65.5%) whereas among consumers of other psychoactive substances, it was necessary to reach the preparation level in the Prochaska algorithm to achieve a success rate greater than 50% (significant interaction: p = 0.02).

CONCLUSION

The psychological preparation of the smoker plays a critical role. The management of smoking cessation must be personalized, especially for consumers of other psychoactive substances and/or smokers with a history of depression.

摘要

引言

本研究旨在确定与戒烟尝试结果相关的因素。

方法

1999年至2009年期间,在克莱蒙费朗的一家戒烟诊所收集了数据(1361名患者)。当患者在戒烟开始6个月后仍保持戒烟状态时,戒烟被视为成功。采用多因素逻辑回归分析来研究戒烟与不同因素之间的关联。

结果

显著因素包括抑郁症病史(校正后比值比=0.57,p=0.003)、初诊时的抑郁状态(校正后比值比=0.64,p=0.005)、其他精神活性物质(校正后比值比=0.52,p<0.0001)、心、肺及耳鼻喉疾病(校正后比值比=0.65,p=0.005)、年龄(校正后比值比=1.04,p<0.0001)、里士满测试(p<0.0001;当患者的动机从不足变为中等时,戒烟频率高出两倍)以及普罗查斯卡算法(p<0.0001;当患者从“未考虑”阶段进入“考虑”阶段时,成功频率高出四倍)。随着年龄增长,里士满测试高分对成功的影响更大(显著交互作用:p=0.01)。在单纯吸烟者中,普罗查斯卡算法中的“考虑”阶段足以获得令人满意的戒烟率(65.5%),而在其他精神活性物质使用者中,有必要达到普罗查斯卡算法中的“准备”阶段才能使成功率超过50%(显著交互作用:p=0.02)。

结论

吸烟者的心理准备起着关键作用。戒烟管理必须个性化,尤其是对于其他精神活性物质使用者和/或有抑郁症病史的吸烟者。

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