Joly Bertrand, Perriot Jean, d'Athis Philippe, Chazard Emmanuel, Brousse Georges, Quantin Catherine
Biostatistics and Bioinformatics (DIM), University Hospital, Dijon, France; Bourgogne Franche-Comté University, Dijon, France.
Dispensaire Emile Roux, Centre d'Aide à I'Arrêt du Tabagisme (IRAAT), Centre de Lutte Anti-Tuberculeuse (CLAT), Clermont-Ferrand, France.
PLoS One. 2017 Oct 11;12(10):e0184800. doi: 10.1371/journal.pone.0184800. eCollection 2017.
The aim of this study was to identify factors associated with the results of smoking cessation attempts.
Data were collected in Clermont-Ferrand from a smoking cessation clinic between 1999 and 2009 (1,361 patients). Smoking cessation was considered a success when patients were abstinent 6 months after the beginning of cessation. Multivariate logistic regression was used to investigate the association between abstinence and different factors.
The significant factors were a history of depression (ORadjusted = 0.57, p = 0.003), state of depression at the initial consultation (ORa = 0.64, p = 0.005), other psychoactive substances (ORa = 0.52, p<0.0001), heart, lung and Ear-Nose-Throat diseases (ORa = 0.65, p = 0.005), age (ORa = 1.04, p<0.0001), the Richmond test (p<0.0001; when the patient's motivation went from insufficient to moderate, the frequency of abstinence was twice as high) and the Prochaska algorithm (p<0.0001; when the patient went from the 'pre-contemplation' to the 'contemplation' level, the frequency of success was four times higher). A high score in the Richmond test had a greater impact on success with increasing age (significant interaction: p = 0.01). In exclusive smokers, the contemplation level in the Prochaska algorithm was enough to obtain a satisfactory abstinence rate (65.5%) whereas among consumers of other psychoactive substances, it was necessary to reach the preparation level in the Prochaska algorithm to achieve a success rate greater than 50% (significant interaction: p = 0.02).
The psychological preparation of the smoker plays a critical role. The management of smoking cessation must be personalized, especially for consumers of other psychoactive substances and/or smokers with a history of depression.
本研究旨在确定与戒烟尝试结果相关的因素。
1999年至2009年期间,在克莱蒙费朗的一家戒烟诊所收集了数据(1361名患者)。当患者在戒烟开始6个月后仍保持戒烟状态时,戒烟被视为成功。采用多因素逻辑回归分析来研究戒烟与不同因素之间的关联。
显著因素包括抑郁症病史(校正后比值比=0.57,p=0.003)、初诊时的抑郁状态(校正后比值比=0.64,p=0.005)、其他精神活性物质(校正后比值比=0.52,p<0.0001)、心、肺及耳鼻喉疾病(校正后比值比=0.65,p=0.005)、年龄(校正后比值比=1.04,p<0.0001)、里士满测试(p<0.0001;当患者的动机从不足变为中等时,戒烟频率高出两倍)以及普罗查斯卡算法(p<0.0001;当患者从“未考虑”阶段进入“考虑”阶段时,成功频率高出四倍)。随着年龄增长,里士满测试高分对成功的影响更大(显著交互作用:p=0.01)。在单纯吸烟者中,普罗查斯卡算法中的“考虑”阶段足以获得令人满意的戒烟率(65.5%),而在其他精神活性物质使用者中,有必要达到普罗查斯卡算法中的“准备”阶段才能使成功率超过50%(显著交互作用:p=0.02)。
吸烟者的心理准备起着关键作用。戒烟管理必须个性化,尤其是对于其他精神活性物质使用者和/或有抑郁症病史的吸烟者。