Mayo Clinic, Scottsdale, AZ, USA.
J Gen Intern Med. 2013 Aug;28(8):1028-34. doi: 10.1007/s11606-012-2249-4.
Nonmedical use of prescription psychostimulants such as methylphenidate and amphetamine salts for the purpose of cognitive enhancement is a growing trend, particularly in educational environments. To our knowledge, no recent studies have evaluated the use of these psychostimulants in a medical academic setting.
To conduct an online census of psychostimulant use among medical students.
In 2011, we conducted a multi-institutional census using a 31-48 item online survey regarding use of prescription psychostimulants.
2,732 actively enrolled medical students at four private and public medical schools in the greater Chicago area.
Prevalence and correlates of psychostimulant use
1,115 (41 %) of students responded to the web-based questionnaire (range 26-47 % among schools). On average, students were 25.1 years of age (SD = 2.7, range 20-49), and single (70 %). Overall, 18 % (198/1,115) of this medical student sample had used prescription psychostimulants at least once in their lifetime, with first use most often in college. Of these, 11 % (117/1,115) of students reported use during medical school (range 7-16 % among schools). Psychostimulant use was significantly correlated with use of barbiturates, ecstasy, and tranquilizers (Pearson's correlation r > 0.5, Student's t-test p < 0.01); male gender (21 % male versus 15 % female, Chi squared p = 0.007); and training at a medical school which by student self-report determined class rank (68 % versus 51 %, Chi-squared p = 0.018). Non-users were more likely to be first year students (Chi-squared p = 0.048) or to have grown up outside of the United States (Chi-squared p = 0.013).
Use of psychostimulants, including use without a prescription, is common among medical students. Further study of the side effects, medical implications, and use during post-graduate medical training and medical practice is needed to inform evidence-based policy.
非医疗用途的处方兴奋剂,如哌醋甲酯和苯丙胺盐,用于认知增强,是一个日益增长的趋势,特别是在教育环境中。据我们所知,最近没有研究评估这些兴奋剂在医学学术环境中的使用情况。
对医学生使用兴奋剂的情况进行在线普查。
在 2011 年,我们使用了一个 31-48 项的在线调查,对四家私立和公立医学院的医学生进行了多机构普查,以了解他们使用处方兴奋剂的情况。
2732 名积极注册的医学生在大芝加哥地区的四所私立和公立医学院就读。
兴奋剂使用的流行率和相关因素。
1115 名(41%)学生回答了基于网络的问卷(四所学校的回答率在 26%到 47%之间)。平均而言,学生年龄为 25.1 岁(标准差 2.7,范围 20-49),单身(70%)。总体而言,18%(198/1115)的医学生样本在他们的一生中至少使用过一次处方兴奋剂,首次使用通常是在大学期间。其中,11%(117/1115)的学生报告在医学院期间使用过兴奋剂(四所学校的报告率在 7-16%之间)。兴奋剂的使用与巴比妥类药物、摇头丸和镇静剂的使用显著相关(皮尔逊相关系数 r > 0.5,学生 t 检验 p < 0.01);男性(21%的男性与 15%的女性,卡方检验 p = 0.007);以及根据学生自我报告的班级排名确定的医学院培训(68%与 51%,卡方检验 p = 0.018)。非使用者更有可能是一年级学生(卡方检验 p = 0.048)或在美国以外长大(卡方检验 p = 0.013)。
医学生使用兴奋剂,包括非处方使用兴奋剂,是很常见的。需要进一步研究其副作用、医学意义以及在毕业后医学培训和医疗实践中的使用情况,以为制定基于证据的政策提供信息。