CLSI 2009 版到 EUCAST 2011 版临床折点变化对革兰氏阴性杆菌多种药物耐药率的影响。
Influence of clinical breakpoint changes from CLSI 2009 to EUCAST 2011 antimicrobial susceptibility testing guidelines on multidrug resistance rates of Gram-negative rods.
机构信息
Institut für Medizinische Mikrobiologie, Universität Zürich, Zürich, Switzerland.
出版信息
J Clin Microbiol. 2013 Jul;51(7):2385-7. doi: 10.1128/JCM.00921-13. Epub 2013 Apr 17.
Abstract
Multidrug resistance (MDR) rates of Gram-negative rods were analyzed comparing CLSI 2009 and EUCAST 2011 antibiotic susceptibility testing guidelines. After EUCAST 2011 was applied, the MDR rates increased for Klebsiella pneumoniae (2.2%), Enterobacter cloacae (1.1%), Pseudomonas aeruginosa (0.7%), and Escherichia coli (0.4%). A total of 24% of Enterobacteriaceae MDR isolates and 12% of P. aeruginosa MDR isolates were categorized as MDR due to breakpoint changes.
摘要
比较 CLSI 2009 年和 EUCAST 2011 年抗生素药敏检测指南，分析革兰氏阴性杆菌的多重耐药（MDR）率。应用 EUCAST 2011 后，肺炎克雷伯菌（2.2%）、阴沟肠杆菌（1.1%）、铜绿假单胞菌（0.7%）和大肠埃希菌（0.4%）的 MDR 率上升。由于折点变化，肠杆菌科 MDR 分离株和 12%的铜绿假单胞菌 MDR 分离株共 24%被归类为 MDR。
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