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Effects of clinical breakpoint changes in CLSI guidelines 2010/2011 and EUCAST guidelines 2011 on antibiotic susceptibility test reporting of Gram-negative bacilli.CLSI 指南 2010/2011 和 EUCAST 指南 2011 中临床折点变化对革兰氏阴性杆菌抗生素药敏试验报告的影响。
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Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.耐多药、广泛耐药和全耐药细菌：获得性耐药的国际专家临时标准定义建议
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Adverse effects of isolation in hospitalised patients: a systematic review.住院患者隔离的不良影响：系统评价。
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Multidrug resistance among gram-negative pathogens that caused healthcare-associated infections reported to the National Healthcare Safety Network, 2006-2008.2006-2008 年全国医疗保健安全网络报告的引起医疗保健相关感染的革兰氏阴性病原体的多药耐药性。
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Stratification of cumulative antibiograms in hospitals for hospital unit, specimen type, isolate sequence and duration of hospital stay.根据医院科室、标本类型、分离株序列和住院时间对医院累积抗菌谱进行分层。
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CLSI 2009 版到 EUCAST 2011 版临床折点变化对革兰氏阴性杆菌多种药物耐药率的影响。

Influence of clinical breakpoint changes from CLSI 2009 to EUCAST 2011 antimicrobial susceptibility testing guidelines on multidrug resistance rates of Gram-negative rods.

机构信息

Institut für Medizinische Mikrobiologie, Universität Zürich, Zürich, Switzerland.

出版信息

J Clin Microbiol. 2013 Jul;51(7):2385-7. doi: 10.1128/JCM.00921-13. Epub 2013 Apr 17.

DOI:10.1128/JCM.00921-13
PMID:23596246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3697730/
Abstract

Multidrug resistance (MDR) rates of Gram-negative rods were analyzed comparing CLSI 2009 and EUCAST 2011 antibiotic susceptibility testing guidelines. After EUCAST 2011 was applied, the MDR rates increased for Klebsiella pneumoniae (2.2%), Enterobacter cloacae (1.1%), Pseudomonas aeruginosa (0.7%), and Escherichia coli (0.4%). A total of 24% of Enterobacteriaceae MDR isolates and 12% of P. aeruginosa MDR isolates were categorized as MDR due to breakpoint changes.

摘要

比较 CLSI 2009 年和 EUCAST 2011 年抗生素药敏检测指南，分析革兰氏阴性杆菌的多重耐药（MDR）率。应用 EUCAST 2011 后，肺炎克雷伯菌（2.2%）、阴沟肠杆菌（1.1%）、铜绿假单胞菌（0.7%）和大肠埃希菌（0.4%）的 MDR 率上升。由于折点变化，肠杆菌科 MDR 分离株和 12%的铜绿假单胞菌 MDR 分离株共 24%被归类为 MDR。