Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, Beijing, China.
Am J Hypertens. 2013 Aug;26(8):997-1004. doi: 10.1093/ajh/hpt050. Epub 2013 Apr 18.
The prevalence of obesity, based on body mass index (BMI), among Chinese children and adolescents has increased for decades, but the relationship between trends in blood pressure (BP) and increasing BMI has not been studied.
BMI and BP measurements of 391,982 children aged 7-17 years were obtained from surveys in 2005 and 2010. The mean change and 95% confidence intervals (CIs) of BP were calculated, and the association between BMI and BP was assessed by using analysis of covariance and direct adjustment with the BMI distribution of 2005 survey.
The mean systolic BP (SBP) and diastolic BP (DBP) increased 1.5 mm Hg (95% CI = 1.4-1.7 mm Hg) and 1.1 mm Hg (95%CI = 1.1-1.2 mm Hg) for boys and 1.2 mm Hg (95% CI = 1.1-1.3 mm Hg) and 1.0 mm Hg (95% CI = 1.0-1.1 mm Hg) for girls from 2005 to 2010, respectively. After adjustment for BMI, SBP and DBP in 2010 were 0.8mm Hg (95% CI = 0.8-0.9mm Hg) and 0.8mm Hg (95% CI = 0.7-0.8mm Hg) higher than in 2005, respectively (all P < 0.01). With adjustment for difference in BMI distribution in 2005 and 2010, the mean increase of SBP decreased by 40.5% and that of DBP by 26.9%.
BP among Chinese children and adolescents was on the rise from 2005 to 2010, which was consistent with the hypothesis that the rise in BP was in part attributable to the rise in BMI.
基于身体质量指数(BMI),中国儿童和青少年的肥胖患病率几十年来一直在上升,但血压(BP)趋势与 BMI 增加之间的关系尚未得到研究。
从 2005 年和 2010 年的调查中获得了 391982 名 7-17 岁儿童的 BMI 和 BP 测量值。计算了 BP 的平均变化和 95%置信区间(CI),并通过协方差分析和直接调整 2005 年调查的 BMI 分布来评估 BMI 与 BP 之间的关系。
男孩的平均收缩压(SBP)和舒张压(DBP)分别增加了 1.5mmHg(95%CI=1.4-1.7mmHg)和 1.1mmHg(95%CI=1.1-1.2mmHg),女孩分别增加了 1.2mmHg(95%CI=1.1-1.3mmHg)和 1.0mmHg(95%CI=1.0-1.1mmHg)。从 2005 年到 2010 年,调整 BMI 后,2010 年的 SBP 和 DBP 分别比 2005 年高 0.8mmHg(95%CI=0.8-0.9mmHg)和 0.8mmHg(95%CI=0.7-0.8mmHg)(均 P<0.01)。调整 2005 年和 2010 年 BMI 分布的差异后,SBP 的平均增幅降低了 40.5%,DBP 的增幅降低了 26.9%。
2005 年至 2010 年,中国儿童和青少年的 BP 呈上升趋势,这与 BP 上升部分归因于 BMI 上升的假设一致。