Kumar Balasubramanian Senthil, Sathasivasubramanian Sankara Pandian
Department of Oral Medicine and Radiology, K.S.R. Institute of Dental Sciences and R.I., Tiruchengode, India.
Indian J Nucl Med. 2012 Jan;27(1):16-9. doi: 10.4103/0972-3919.108832.
The aim of the study was to evaluate the salivary gland dysfunction in a patient with uncontrolled type 2 diabetes using salivary gland scintigraphy.
patients included in the study were 32 uncontrolled type 2 diabetic and 30 normal healthy individuals. Patients having any other systemic(or) nervous illness(or) taking medications that could affect the normal functioning of the salivary gland were excluded from the study. The salivary gland scintigraphy was performed, with radioactivity measured at 1(st), 20(th), and 40(th) minutes. Twenty minutes after the injection, vitamin C chewable tablet was given to stimulate the secretion and continued until the end of the study period (40min). The data were replayed and regions of interest were chosen over four salivary glands to obtain the uptake ratio (UR) and excretory ratio(ER) of the salivary glands.
The scintigraphic total URand ER in diabetic and control groups was compared. The values in these two categories showed decrease in both UR and ER in diabetic patients, when compared to control patients.
The result of this study suggests that salivary gland scintigraphy plays a significant role in the evaluation of salivary gland dysfunction in type 2 diabetic patients.
本研究旨在利用唾液腺闪烁扫描术评估一名2型糖尿病控制不佳患者的唾液腺功能障碍。
纳入研究的患者有32名2型糖尿病控制不佳患者和30名正常健康个体。患有任何其他全身性（或）神经疾病（或）正在服用可能影响唾液腺正常功能药物的患者被排除在研究之外。进行唾液腺闪烁扫描术，在第1、20和40分钟测量放射性。注射后20分钟，给予维生素C咀嚼片以刺激分泌，并持续至研究期结束（40分钟）。回放数据并在四个唾液腺上选择感兴趣区域，以获得唾液腺的摄取率（UR）和排泄率（ER）。
比较糖尿病组和对照组的闪烁扫描总UR和ER。与对照组患者相比，这两类患者的值显示糖尿病患者的UR和ER均降低。
本研究结果表明，唾液腺闪烁扫描术在评估2型糖尿病患者唾液腺功能障碍方面发挥着重要作用。
