碘-131间碘苄胍单光子发射计算机断层扫描/计算机断层扫描在神经内分泌肿瘤诊断中的应用
Iodine-131 meta-iodobezylguanidine single photon emission computed tomography/computerized tomography in diagnosis of neuro-endocrine tumors.
作者信息
Harisankar Chidambaram Natrajan Balasubramanian, Mittal Bhagwant Rai, Bhattacharya Anish, Kashyap Raghava, Bhansali Anil
机构信息
Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
出版信息
Indian J Nucl Med. 2012 Jan;27(1):55-8. doi: 10.4103/0972-3919.108877.
Metaiodobenzyl guanidine (MIBG) is a derivative of guanethidine and acts as an analogue of nor-epinephrine and is widely used in the imaging of tumors of neuro-endocrine origin. Iodine-123 MIBG has ideal imaging characteristics but is expensive with limited availability. Iodine-131 MIBG is widely used in India and is cheap. Hybrid single photon emission computed tomography (SPECT)/computerized tomography (CT) allows for anatomico-functional imaging and is being tried in MIBG studies. However, the experience with I-131 MIBG is limited. We present a pictorial assay of I-131 MIBG SPECT/CT findings in various MIBG avid tumors.
间碘苄胍（MIBG）是胍乙啶的衍生物，可作为去甲肾上腺素的类似物，广泛用于神经内分泌起源肿瘤的成像。碘-123 MIBG具有理想的成像特性，但价格昂贵且供应有限。碘-131 MIBG在印度被广泛使用且价格便宜。杂交单光子发射计算机断层扫描（SPECT）/计算机断层扫描（CT）可进行解剖功能成像，目前正在MIBG研究中试用。然而，碘-131 MIBG的经验有限。我们展示了碘-131 MIBG SPECT/CT在各种摄取MIBG的肿瘤中的图像分析结果。
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