Center for Pregnant Women with Diabetes, Rigshospitalet University Hospital, Copenhagen, Denmark.
Acta Obstet Gynecol Scand. 2013 Jul;92(7):739-45. doi: 10.1111/aogs.12152. Epub 2013 May 15.
The establishment of universal diagnostic guidelines for gestational diabetes mellitus has been a long time coming. The lack of consensus and uniformity in procedures for diagnosing this disease has been a problem ever since its existence was recognized. The USA, European countries, and Australia have each developed their own guidelines through the years, all based either on the maternal risk of subsequent diabetes, on arbitrary statistics, or on studies conducted on non-pregnant women. None of these guidelines have been based on risk for perinatal complications. Recently, the Hyperglycemia and Adverse Pregnancy Outcomes study demonstrated that maternal hyperglycemia is associated with perinatal risk in a linear way with no obvious threshold. The International Association of Diabetes and Pregnancy Study Group has translated these results into clinical practice by proposing new diagnostic criteria for gestational diabetes mellitus, based for the first time on perinatal outcome.
制定通用的妊娠期糖尿病诊断指南由来已久。自认识到这种疾病以来，其诊断程序缺乏共识和统一性一直是一个问题。多年来，美国、欧洲国家和澳大利亚各自制定了自己的指南，这些指南都是基于母亲日后患糖尿病的风险、任意的统计数据，或者是对非孕妇进行的研究。这些指南都没有基于围产期并发症的风险。最近，高血糖与不良妊娠结局研究表明，母亲的高血糖与围产期风险呈线性关系，没有明显的阈值。国际妊娠合并糖尿病研究组织将这些结果转化为临床实践，首次提出了基于围产结局的妊娠期糖尿病新的诊断标准。
