根龋的预防：关于一级和二级预防剂的文献综述
Prevention of root caries: a literature review of primary and secondary preventive agents.
作者信息
Gluzman Rima, Katz Ralph V, Frey Barbara J, McGowan Richard
机构信息
Department of Epidemiology and Health Promotion, NYU College of Dentistry, NY, USA.
出版信息
Spec Care Dentist. 2013 May-Jun;33(3):133-40. doi: 10.1111/j.1754-4505.2012.00318.x. Epub 2012 Dec 10.
PURPOSE
This literature review summarizes the effectiveness of the seven leading root caries preventive agents and provides recommendations for use of those agents in clinical practice with older adults and vulnerable elderly.
METHOD
Studies were eligible if they assessed the effectiveness of either fluoride, chlorhexidine, xylitol, amorphous calcium phosphate, sealants, saliva stimulators, or silver diamine fluoride to prevent/control root caries in an English language articles between 1979 and 2010.
RESULTS
In the 31 eligible studies, the most effective primary (1°) prevention agents had reductions in RC incidence ranging from 72% to nearly 200% as compared to a placebo while for secondary (2°) prevention, the best agents demonstrated arrest rates between 67 and 80%.
CONCLUSION
For 1° prevention of root caries the recommended "best choice" is a 38% Silver Diamine Fluoride solution professionally applied annually, while for the 2° prevention of root caries, the recommended "best choice" is a 22,500 ppm Sodium Fluoride varnish professionally applied every 3 months.
目的
本文献综述总结了七种主要的根龋预防剂的有效性，并为这些药剂在老年和弱势老年人临床实践中的使用提供建议。
方法
如果研究评估了氟化物、氯己定、木糖醇、无定形磷酸钙、窝沟封闭剂、唾液刺激剂或氟化银胺预防/控制根龋的有效性，且研究以英文发表于1979年至2010年之间，则这些研究符合要求。
结果
在31项符合要求的研究中，与安慰剂相比，最有效的一级预防剂使根龋发病率降低了72%至近200%，而对于二级预防，最佳药剂的患龋率控制在67%至80%之间。
结论
对于根龋的一级预防，推荐的“最佳选择”是每年专业应用一次38%的氟化银胺溶液，而对于根龋的二级预防，推荐的“最佳选择”是每三个月专业应用一次含22,500 ppm氟化钠的清漆。
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