Baca Pilar, Clavero Javier, Baca Adela P, González-Rodríguez M Paloma, Bravo Manuel, Valderrama Mariano J
School of Dentistry, University of Granada, Spain.
J Dent. 2009 Sep;37(9):679-85. doi: 10.1016/j.jdent.2009.05.001. Epub 2009 May 13.
Little is known about the effect of Cervitec, a chlorhexidine-thymol varnish, on root caries. Our objective was to determine whether a 3-monthly application of Cervitec over 1 year would limit the progress of existing root caries lesions and reduce the incidence of dental root caries in a group of dentate institutionalized elderly, as a complement to their usual oral hygiene practices.
A double-blind randomized clinical trial was conducted in 68 subjects (34 per group) in two residences in Almería (Spain). Twenty-one subjects with 60 root caries lesions and 25 with 65 lesions, in the Cervitec and placebo groups, respectively, completed the study. Varnishes were applied twice in the first week, 1 month later, and every 3 months until the end of the study. Clinical parameters associated with established lesions were determined at baseline and after 6 and 12 months, as was the incidence of root caries lesions.
The clinical evolution of lesions was significantly better in the Cervitec group as opposed to the placebo group in terms of width, height, color, and texture. The increase in root caries was significantly lower (p=0.039) in the Cervitec group.
According to these results, Cervitec may help to control established root lesions and reduce the incidence of root caries lesion among institutionalized elderly.
关于洗必泰百里酚涂剂Cervitec对根龋的影响,目前所知甚少。我们的目的是确定在一组有牙的机构养老老年人中,每3个月应用一次Cervitec,持续1年,是否会限制现有根龋损害的进展,并降低牙根部龋的发生率,作为他们日常口腔卫生措施的补充。
在西班牙阿尔梅里亚的两个养老院对68名受试者(每组34名)进行了一项双盲随机临床试验。Cervitec组和安慰剂组分别有21名和25名患有根龋损害的受试者完成了研究,Cervitec组有60个根龋损害,安慰剂组有65个根龋损害。在研究的第一周涂两次涂剂,1个月后再涂一次,此后每3个月涂一次,直至研究结束。在基线、6个月和12个月时,测定与已有的损害相关的临床参数以及根龋损害的发生率。
在损害的宽度、高度、颜色和质地方面,Cervitec组的损害临床进展明显优于安慰剂组。Cervitec组根龋的增加明显更低(p=0.039)。
根据这些结果,Cervitec可能有助于控制已有的根部损害,并降低机构养老老年人中根龋损害的发生率。