Department of Chemistry, Tsinghua University, Beijing 100084, China.
Anal Chim Acta. 2013 May 7;776:69-73. doi: 10.1016/j.aca.2013.03.033. Epub 2013 Mar 21.
Compound 1 was facilely synthesized through a one step reaction from commercially available materials. As a sensitive and selective "turn-on" fluorescent chemosensor for Zn(II), 1 exhibits a 40-fold fluorescence enhancement response to Zn(II) over other physiological relevant metal ions in aqueous solution at neutral pH. Furthermore, 1 could be efficiently delivered to live cells for bioimaging of Zn(II).
化合物 1 可由市售原料通过一步反应简便合成。作为对 Zn(II)具有灵敏选择性的“开启型”荧光化学传感器，1 在中性 pH 的水溶液中对 Zn(II)的荧光增强响应可达其他生理相关金属离子的 40 倍。此外，1 可有效地递送至活细胞中，用于 Zn(II)的生物成像。
