Zhang Ming-chang, Bian Fang
Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430002, China.
Zhonghua Yan Ke Za Zhi. 2013 Jan;49(1):6-7.
Dry eye disease is a common ocular surface disorder among ophthalmological conditions. Treatment generally focuses on tear supplement by topical artificial tears but less focus on the immunological changes in the pathogenesis of the dry eye. As our understanding of the pathology of the disease improves, new definitions are being developed. It turns out that inflammation, and dry eye accompanied relationship can not be ignored. Topical corticosteroid therapy for dry eye should be more cautioned and topical use of Cyclosporin A (CsA) and nonsteroidal anti-inflammatory drugs (NSAIDs) require more attention. In order to standardize management strategies for dry eye, multi-center studies for the link between inflammation and dry eye are needed, and epidemiological survey should be performed.
干眼疾病是眼科疾病中一种常见的眼表疾病。治疗通常侧重于通过局部使用人工泪液补充泪液，但较少关注干眼发病机制中的免疫变化。随着我们对该疾病病理学认识的提高，新的定义正在不断形成。事实证明，炎症与干眼的伴随关系不容忽视。干眼局部应用皮质类固醇疗法应更加谨慎，局部使用环孢素A（CsA）和非甾体类抗炎药（NSAIDs）需要更多关注。为了规范干眼的管理策略，需要开展关于炎症与干眼之间联系的多中心研究，并进行流行病学调查。
