Ausman J I, Diaz F G, Sadasivan B, Gonzeles-Portillo M, Malik G M, Deopujari C E
Henry Ford Hospital Division, Department of Neurological Surgery, Detroit, Michigan 48202.
Surg Neurol. 1990 Jul;34(1):8-15. doi: 10.1016/0090-3019(90)90166-m.
The surgical management of 62 anterior circulation giant intracranial aneurysms is presented. Women were affected three times as frequently as men. Thirty-two patients presented with local mass effect, which was the most common mode of presentation, while 26 patients had subarachnoid hemorrhage. Three patients presented with transient ischemic attacks and three patients presented with seizures. In 16 cases the giant intracranial aneurysm involved the cavernous sinus and indirect surgery was performed. Ten patients were treated with extracranial-intracranial bypass and gradual occlusion of the proximal internal carotid artery. Six patients were treated with extracranial-intracranial bypass and trapping of the aneurysm (sudden occlusion of internal carotid artery). Sudden occlusion was poorly tolerated, and 50% of the patients developed ischemic complications. In 46 cases of giant intracranial aneurysm without involvement of the cavernous sinus, direct surgery was undertaken. In 31 patients the aneurysm could be clipped without compromise to the surrounding vessels. In 15 patients there was compromise of surrounding vessels or the aneurysm sac was excised and so microvascular reconstruction was needed. Local intracranial reconstruction was preferred whenever feasible. The results of patients who needed reconstruction were similar to those who did not need reconstruction. Overall, 84% of patients had an excellent or good outcome after surgery. The mortality was 5%.
本文介绍了62例前循环巨大颅内动脉瘤的手术治疗情况。女性患者的发病率是男性的三倍。32例患者表现为局部占位效应,这是最常见的表现形式,而26例患者发生蛛网膜下腔出血。3例患者出现短暂性脑缺血发作,3例患者出现癫痫发作。16例巨大颅内动脉瘤累及海绵窦,行间接手术。10例患者采用颅外-颅内血管搭桥术并逐渐闭塞颈内动脉近端。6例患者采用颅外-颅内血管搭桥术并夹闭动脉瘤(颈内动脉突然闭塞)。突然闭塞耐受性差,50%的患者出现缺血性并发症。46例未累及海绵窦的巨大颅内动脉瘤患者行直接手术。31例患者的动脉瘤可以夹闭而不影响周围血管。15例患者周围血管受累或切除动脉瘤囊,因此需要微血管重建。只要可行,优先选择局部颅内重建。需要重建的患者与不需要重建的患者结果相似。总体而言,84%的患者术后预后良好或优秀。死亡率为5%。