Marc and Ruti Bell Vascular Biology and Disease Program, Leon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, NY 10029, USA.
Immunity. 2013 Apr 18;38(4):628-30. doi: 10.1016/j.immuni.2013.03.006.
Why patients with chronic kidney disease have elevated cardiovascular risk remains elusive. In this issue of Immunity, Speer et al. (2013) show that natural modification of high density lipoprotein promotes hypertension through a Toll-like receptor-dependent mechanism.
为什么慢性肾病患者的心血管风险会升高仍然难以捉摸。在本期《免疫》杂志中,Speer 等人(2013)表明,高密度脂蛋白的自然修饰通过 Toll 样受体依赖的机制促进高血压。