Department of Cardiothoracic Surgery, Cork University Hospital, Wilton, Cork, Ireland; Cork Cancer Research Centre, Bioscience Institute, University College Cork, Cork, Ireland.
Cancer Treat Rev. 2013 Dec;39(8):862-71. doi: 10.1016/j.ctrv.2013.03.007. Epub 2013 Apr 17.
Lung cancer remains the most common cancer diagnosed worldwide and has one of the lowest survival rates of all cancers. Surgery remains the only curative treatment option but because most patients are either diagnosed at advanced stages or are unfit for surgery, less than a third of all lung cancer patients will undergo a surgical resection. Thermal ablation has emerged as an alternative option in patients who are unfit to undergo surgery. Thermal ablative therapies used in clinical practice to date include Radiofrequency Ablation (RFA), Microwave Ablation (MWA) and Cryoablation This article will focus on the advantages and limitations of thermal ablative therapy and investigates the potential of a relatively new treatment modality, Electrochemotherapy (ECT), as a novel treatment for lung cancer.
肺癌仍然是全球最常见的癌症，也是所有癌症中存活率最低的癌症之一。手术仍然是唯一的治愈性治疗选择，但由于大多数患者要么被诊断为晚期，要么不适合手术，因此只有不到三分之一的肺癌患者会接受手术切除。热消融已成为不适合手术的患者的另一种选择。迄今为止，临床实践中使用的热消融治疗方法包括射频消融（RFA）、微波消融（MWA）和冷冻消融。本文将重点介绍热消融治疗的优缺点，并研究一种相对较新的治疗方式——电化学疗法（ECT）作为肺癌治疗的新方法的潜力。
