SCAN Research and Teaching Unit, School of Psychology, University of Sydney, Australia.
Drug Alcohol Depend. 2013 Sep 1;132(1-2):395-8. doi: 10.1016/j.drugalcdep.2013.02.025. Epub 2013 Apr 16.
Past research has highlighted an important role of the autonomic nervous system in alcohol dependence and capacity for self-regulation. While previous studies have examined alcohol dependent inpatients, it remains unclear whether resting-state HRV, a potential psychophysiological marker of ones capacity for self-regulation, is related to craving in patients who currently consume alcohol. Thus, the aim of the present study was to determine whether HRV predicts alcohol craving in dependent individuals in the community.
Resting-state HRV and alcohol craving, as indexed by the obsessive compulsive drinking scale, were assessed in 26 alcohol dependent outpatients.
Results supported hypotheses indicating that HRV accounts for an additional 12.1% of the variance in craving after controlling for age, anxiety and levels of alcohol consumption. Here we show for the first time that resting-state HRV predicts craving in alcohol dependent outpatients.
Results provide important new evidence for a role of the autonomic nervous system in the maintenance of dependence disorders.
过去的研究强调了自主神经系统在酒精依赖和自我调节能力中的重要作用。虽然以前的研究已经检查了酒精依赖的住院患者,但目前尚不清楚静息状态心率变异性(自主神经系统功能的一个潜在心理生理学标志物)是否与当前饮酒患者的渴望有关。因此,本研究的目的是确定静息状态心率变异性是否可以预测社区中依赖个体的酒精渴望。
在 26 名酒精依赖的门诊患者中评估了静息状态心率变异性和酒精渴望(以强迫性饮酒量表为指标)。
结果支持了以下假设,即控制年龄、焦虑和饮酒水平后,心率变异性解释了渴望的 12.1%的额外差异。这里我们首次表明,静息状态心率变异性可以预测酒精依赖门诊患者的渴望。
结果为自主神经系统在维持依赖障碍中的作用提供了重要的新证据。