Department of Analytical Chemistry I3A, University of Zaragoza, Campus Rio Ebro, Zaragoza, Spain.
Anal Chim Acta. 2013 May 2;775:14-24. doi: 10.1016/j.aca.2013.02.028. Epub 2013 Feb 28.
Packaged food can contain non-intentionally added substances (NIAS) as a result of reaction and degradation processes or the presence of impurities in the raw materials used for the packaging production. This manuscript reviews the evidence of NIAS and their possible origin. One of the most challenging and difficult tasks when a sample of packaging materials arrives at the laboratory is knowing the procedure to apply for identifying the unknown compounds. This work proposes an analytical procedure for sample treatment, applicable to polymers as well as to migration samples, and for NIAS identification. The identification protocol comprises the determination of both volatile and non-volatile compounds. A review is presented of the most novel analytical techniques used for identification purposes, particularly high resolution mass spectrometry (HRMS).
包装食品可能由于反应和降解过程或包装生产所用原材料中的杂质而含有非故意添加的物质（NIAS）。本文综述了 NIAS 的证据及其可能的来源。当包装材料样品到达实验室时，最具挑战性和困难的任务之一是知道应用哪种程序来识别未知化合物。这项工作提出了一种适用于聚合物以及迁移样品的样品处理分析程序，以及用于 NIAS 鉴定的程序。鉴定方案包括挥发性和非挥发性化合物的测定。本文还综述了用于鉴定目的的最新型分析技术，特别是高分辨率质谱（HRMS）。
