Thyroid Cancer Interdisciplinary Program, Division of Endocrine Surgery, NYU Langone Medical Center, New York, NY, USA.
Oral Oncol. 2013 Jul;49(7):711-21. doi: 10.1016/j.oraloncology.2013.03.437. Epub 2013 Apr 17.
Recent molecular studies have described a number of abnormalities associated with the pathogenesis of thyroid carcinoma. These distinct molecular events are often associated with specific stages of tumor development and may serve as prognostic factors and therapeutic targets. A better understanding of the mechanisms involved in thyroid cancer pathogenesis, will hopefully help translate these discoveries to improved patient care.
最近的分子研究描述了许多与甲状腺癌发病机制相关的异常。这些不同的分子事件通常与肿瘤发展的特定阶段相关,并且可以作为预后因素和治疗靶点。更好地了解甲状腺癌发病机制中涉及的机制,有望帮助将这些发现转化为改善患者护理的方法。