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甲状腺髓样癌：遗传学进展、治疗建议及持续性降钙素血症患者的处理方法

Medullary thyroid carcinoma: genetic advances, treatment recommendations, and the approach to the patient with persistent hypercalcitoninemia.

作者信息

Chi D D, Moley J F

机构信息

Division of General Surgery, Department of Surgery, Washington University School of Medicine, Saint Louis, Missouri, USA.

出版信息

Surg Oncol Clin N Am. 1998 Oct;7(4):681-706.

PMID:9735129
Abstract

Medullary thyroid cancer is a tumor of the thyroid C cells that occurs in sporadic and hereditary clinical settings. Genetic testing of at-risk individuals is available and has been applied to patient management. Plasma calcitonin levels are a sensitive marker for the presence of disease. Surgery offers the best hope for cure and also is an effective modality for managing metastatic and recurrent disease.

摘要

甲状腺髓样癌是一种发生于甲状腺C细胞的肿瘤，见于散发性和遗传性临床情况。对高危个体可进行基因检测，且该检测已应用于患者管理。血浆降钙素水平是疾病存在的敏感标志物。手术提供了治愈的最大希望，也是治疗转移性和复发性疾病的有效方式。

相似文献

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Medullary thyroid carcinoma: genetic advances, treatment recommendations, and the approach to the patient with persistent hypercalcitoninemia.甲状腺髓样癌：遗传学进展、治疗建议及持续性降钙素血症患者的处理方法
Surg Oncol Clin N Am. 1998 Oct;7(4):681-706.
2
Medullary thyroid cancer.甲状腺髓样癌
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引用本文的文献

1
Sporadic medullary thyroid carcinoma with a pedunculated intraluminal internal jugular vein recurrence: A case report and literature review.伴有带蒂腔内颈内静脉复发的散发性甲状腺髓样癌：一例报告及文献复习
Int J Surg Case Rep. 2012;3(2):92-6. doi: 10.1016/j.ijscr.2011.11.005. Epub 2011 Nov 22.
2
Multi-targeted approach in the treatment of thyroid cancer.甲状腺癌治疗中的多靶点方法。
Minerva Chir. 2010 Feb;65(1):59-69.
3
A case of spurious hypercalcitoninemia: a cautionary tale on the use of plasma calcitonin assays in the screening of patients with thyroid nodules for neoplasia.
一例假性高降钙素血症：关于在甲状腺结节患者肿瘤筛查中使用血浆降钙素检测的警示故事。
J Endocrinol Invest. 2001 May;24(5):361-9. doi: 10.1007/BF03343874.
4
Treatment of advanced medullary thyroid cancer with an alternating combination of doxorubicin-streptozocin and 5 FU-dacarbazine. Groupe d'Etude des Tumeurs à Calcitonine (GETC).采用阿霉素-链脲佐菌素与5-氟尿嘧啶-达卡巴嗪交替联合方案治疗晚期甲状腺髓样癌。降钙素瘤研究组（GETC）。
Br J Cancer. 2000 Sep;83(6):715-8. doi: 10.1054/bjoc.2000.1314.