Lorenz C, Wack R, Mau H
Kinderchirurgische Abteilung, Humboldt-Universität zu Berlin.
Z Kinderchir. 1990 Apr;45(2):92-7. doi: 10.1055/s-2008-1042557.
Morphological changes of the oesophageal wall, induced by injection sclerotherapy of oesophageal varices, may produce functional disturbances which are difficult to evaluate especially in children. Therefore manometric studies in 33 consecutive patients with portal hypertension (age: 2-18 years) were performed and functional parameters as of the oesophagus and oesophageal sphincter were recorded in different stages of treatment. The results were compared to findings in healthy children. From our studies we could conclude that functional disturbances seen in sclerolised patients must be set in relation to functional changes which we could see in patients without treatment of oesophageal varices. Endosclerosis affects essential parameters of oesophageal function; however, a large reversibility after termination of the treatment could be documented. The clinical relevance of the recorded findings and the diagnostic value of oesophageal manometry are discussed.
食管静脉曲张注射硬化疗法引起的食管壁形态学改变，可能会产生功能障碍，尤其是在儿童中，这种功能障碍很难评估。因此，对33例连续的门静脉高压患者（年龄2至18岁）进行了测压研究，并在治疗的不同阶段记录了食管和食管括约肌的功能参数。将结果与健康儿童的检查结果进行了比较。从我们的研究中可以得出结论，硬化治疗患者中出现的功能障碍必须与未治疗食管静脉曲张的患者中可见的功能变化相关联。内镜硬化治疗会影响食管功能的基本参数；然而，治疗结束后可记录到很大程度的可逆性。文中讨论了所记录结果的临床相关性以及食管测压的诊断价值。
