Otani H, Mune M
Age (Omaha). 1998 Jul;21(3):105-8. doi: 10.1007/s11357-998-0016-6.
There is an increasing number of elderly patients with glomerulonephritis. A number of reports regarding renal function [1-9] and morphology [10-13] in aged people have been published. However, few studies have been reported on the effect of glomerulonephritis on the kidneys of aged patients. Recently, some articles concerning renal function and histological changes in aged nephritic patients were reported [14]. Several reports about the effects of aging in an experimental kidney disease model [15-23] and on cultured renal cells [22, 24, 25] have been published. This review will focus mainly on the mechanisms of the decrease in renal function and morphological changes with aging.
患有肾小球肾炎的老年患者数量正在增加。关于老年人肾功能[1 - 9]和形态学[10 - 13]的一些报告已经发表。然而，关于肾小球肾炎对老年患者肾脏影响的研究报道很少。最近，有一些关于老年肾病患者肾功能和组织学变化的文章被报道[14]。关于衰老在实验性肾脏疾病模型[15 - 23]以及对培养的肾细胞[22, 24, 25]中影响的一些报告也已发表。本综述将主要关注肾功能下降和衰老相关形态学变化的机制。
