Erdem Elif, Kocabas Emine, Taylan Sekeroglu Hande, Ozgür Ozlem, Yagmur Meltem, Ersoz T Reha
Ophthalmology Department, Cukurova University Faculty of Medicine, Balcali Saricam, Adana 01330, Turkey.
Case Rep Ophthalmol Med. 2013;2013:621952. doi: 10.1155/2013/621952. Epub 2013 Mar 28.
A 7-year-old girl had presented with high body temperature and joint pain which continued for 3 days. Because of the prolonged history of unexplained fever, rash, bilateral nonpurulent conjunctival injection, oropharyngeal erythema, strawberry tongue, and extreme of age, incomplete Kawasaki disease was considered and started on an intravenous immunoglobulin infusion. Six days after this treatment, patient was referred to eye clinic with decreased vision and photophobia. Visual acuity was reduced to 20/40 in both eyes. Slit-lamp examination revealed bilateral diffuse corneal punctate epitheliopathy and anterior stromal haze. Corneal epitheliopathy seemed like crystal deposits. One day after presentation, mild anterior uveitis was added to clinical picture. All ocular findings disappeared in one week with topical steroid and unpreserved artificial tear drops. We present a case who was diagnosed as incomplete Kawasaki disease along with bilateral diffuse crystalline-like keratopathy. We supposed that unusual ocular presentation may be associated with intravenous immunoglobulin treatment.
一名7岁女孩出现高热和关节疼痛，持续了3天。由于存在无法解释的长期发热、皮疹、双侧非脓性结膜充血、口咽红斑、草莓舌以及年龄因素，考虑为不完全川崎病，并开始静脉输注免疫球蛋白。治疗6天后，患者因视力下降和畏光被转诊至眼科门诊。双眼视力降至20/40。裂隙灯检查显示双侧弥漫性角膜点状上皮病变和前基质混浊。角膜上皮病变看起来像晶体沉积。就诊1天后，临床症状中又出现了轻度前葡萄膜炎。使用局部类固醇和无防腐剂人工泪液滴眼后，所有眼部症状在1周内消失。我们报告一例被诊断为不完全川崎病并伴有双侧弥漫性晶体样角膜病变的病例。我们推测这种不寻常的眼部表现可能与静脉输注免疫球蛋白治疗有关。
