Ninomiya Shigeo, Sonoda Kazuya, Shiroshita Hidefumi, Bandoh Toshio, Arita Tsuyoshi
Department of Surgery, Arita Gastrointestinal Hospital, 1-2-6 Maki, Oita 870-0294, Japan.
Case Rep Surg. 2013;2013:560712. doi: 10.1155/2013/560712. Epub 2013 Mar 27.
Invasive micropapillary carcinoma (IMPC) of the breast, urinary bladder, ovary, and colon has been reported. However, few reports have described IMPC of the stomach. In addition, IMPC has been described as a histological indicator for lymphatic invasion and nodal metastasis, resulting in poor prognosis. We report a case of 5-year survival after surgery for IPMC of the stomach. A 69-year-old woman was admitted to our hospital with symptoms of upper abdominal pain. Upper gastrointestinal endoscopy revealed a tumor at the antrum of the stomach. Histological examination of the biopsy specimen indicated poorly differentiated adenocarcinoma. The patient underwent distal gastrectomy with lymph node dissection. Microscopic examination of the specimen revealed that the tumor consisted of an invasive micropapillary component. Carcinoma cell clusters were floating in the clear spaces. The patient recovered uneventfully and remains alive without recurrence 5 years after surgery.
乳腺、膀胱、卵巢和结肠的浸润性微乳头状癌(IMPC)已有报道。然而,关于胃IMPC的报道较少。此外,IMPC被认为是淋巴浸润和淋巴结转移的组织学指标,预后较差。我们报告一例胃IMPC术后生存5年的病例。一名69岁女性因上腹部疼痛症状入院。上消化道内镜检查发现胃窦部有一个肿瘤。活检标本的组织学检查显示为低分化腺癌。患者接受了远端胃切除术及淋巴结清扫术。标本的显微镜检查显示肿瘤由浸润性微乳头状成分组成。癌细胞簇漂浮在透明间隙中。患者术后恢复顺利,术后5年仍存活且无复发。