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低强度激光疗法对瘢痕组织的疗效。

Efficacy of low-level laser therapy on scar tissue.

作者信息

Freitas Carla P, Melo Cristina, Alexandrino Ana M, Noites Andreia

机构信息

Department of Physiotherapy, School of Allied Health Sciences ESTSP Oporto Polytechnic Institute, Vila Nova de Gaia, Portugal.

出版信息

J Cosmet Laser Ther. 2013 Jun;15(3):171-6. doi: 10.3109/14764172.2013.769272.

Abstract

BACKGROUND

Physiotherapy has a very important role in the maintenance of the integumentary system integrity. There is very few evidence in humans. Nevertheless, there are some studies about tissue regeneration using low-level laser therapy (LLLT).

AIM

To analyze the effectiveness of LLLT on scar tissue.

METHODS

Seventeen volunteers were stratified by age of their scars, and then randomly assigned to an experimental group (EG) - n = 9 - and a placebo group (PG) - n = 8. Fifteen sessions were conducted to both the groups thrice a week. However, in the PG, the laser device was switched off. Scars' thickness, length, width, macroscopic aspect, pain threshold, pain perception, and itching were measured.

RESULTS

After 5 weeks, there were no statistically significant differences in any variable between both the groups. However, analyzing independently each group, EG showed a significant improvement in macroscopic aspect (p = 0.003) using LLLT. Taking into account the scars' age, LLLT showed a tendency to decrease older scars' thickness in EG.

CONCLUSION

The intervention with LLLT appears to have a positive effect on the macroscopic scars' appearance, and on old scars' thickness, in the studied sample. However, it cannot be said for sure that LLLT has influence on scar tissue.

摘要

背景

物理治疗在维持皮肤系统完整性方面具有非常重要的作用。在人体中这方面的证据非常少。然而,有一些关于使用低强度激光疗法(LLLT)进行组织再生的研究。

目的

分析低强度激光疗法对瘢痕组织的有效性。

方法

17名志愿者按瘢痕年龄分层,然后随机分为实验组(EG)——n = 9——和安慰剂组(PG)——n = 8。两组均每周进行三次,共进行15次治疗。然而,在安慰剂组中,激光设备处于关闭状态。测量瘢痕的厚度、长度、宽度、宏观外观、疼痛阈值、疼痛感知和瘙痒情况。

结果

5周后,两组之间在任何变量上均无统计学显著差异。然而,单独分析每组时,实验组使用低强度激光疗法在宏观外观上有显著改善(p = 0.003)。考虑到瘢痕的年龄,低强度激光疗法在实验组中显示出使较老瘢痕厚度降低的趋势。

结论

在所研究的样本中,低强度激光疗法干预似乎对宏观瘢痕外观以及老瘢痕厚度有积极影响。然而,不能肯定地说低强度激光疗法对瘢痕组织有影响。

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