Alsharnoubi Jehan, Mohamed Omnia, Fawzy Mary
Pediatrics Department, National Institute of Laser Enhanced Sciences (N.I.L.E.S), Cairo University, House 2 Street 6 Zahraa Helwan, Cairo, Egypt.
Pediatrics Department, Aboelreesh Hospital, Cairo, Egypt.
Lasers Med Sci. 2018 Apr;33(3):497-501. doi: 10.1007/s10103-017-2387-3. Epub 2017 Nov 24.
The management of burn scars has become one of the major clinical challenges in the developing countries which involve enormous treatment cost; this needs new methods for better cost benefit relationship. The objective of the study is to analyze the effectiveness of low-level laser therapy on post-burn scar tissue in children. A randomized controlled study included 15 children, ranging from 2 to 10 years of age, presenting with burn scars. They received diode laser and topical treatment. Each scar was divided into two halves. One half was treated with laser therapy and topical treatment (study area), and the other half was treated with topical treatment only (control area). The children were evaluated before and after 3 months of the study by Vancouver Scar Scale (VSS), ultrasonography (U/S), and laser Doppler perfusion imaging. Significant improvement was reported in the studied area compared to the control area for patients with P values (P = 0.005) and (P = 0.0001) for VSS and U/S scores, respectively. No difference was detected for blood perfusion to the scar between both areas (P = 0.18). In addition, no adverse effect was reported. Photobiomodulation is an efficient and safe therapeutic modality for post-burn hypertrophic scars in children and should be considered a part of combination therapy for better results.
烧伤瘢痕的治疗已成为发展中国家面临的主要临床挑战之一,其治疗成本巨大;这需要新的方法来实现更好的成本效益关系。本研究的目的是分析低强度激光疗法对儿童烧伤后瘢痕组织的有效性。一项随机对照研究纳入了15名年龄在2至10岁之间的烧伤瘢痕患儿。他们接受了二极管激光和局部治疗。每个瘢痕被分成两半。一半接受激光治疗和局部治疗(研究区域),另一半仅接受局部治疗(对照区域)。在研究开始前和3个月后,通过温哥华瘢痕量表(VSS)、超声检查(U/S)和激光多普勒血流成像对患儿进行评估。与对照区域相比,研究区域的患儿在VSS和U/S评分方面分别有显著改善,P值分别为(P = 0.005)和(P = 0.0001)。两个区域瘢痕的血液灌注未检测到差异(P = 0.18)。此外,未报告不良反应。光生物调节是治疗儿童烧伤后增生性瘢痕的一种有效且安全的治疗方式,为获得更好的效果,应将其视为联合治疗的一部分。