Cirio A, Boivin R
Laboratoire de physiologie et pharmacodynamie, Ecole nationale vétérinaire de Lyon, Marcy-l'Etoile, France.
Ann Rech Vet. 1990;21(2):167-70.
In sheep fed low-protein diets, renal PAH and inulin extractions are not affected by the fall in plasma urea level or in the renal plasma flow itself. The noted reduction in glomerular filtration rate is not due to a preglomerular shunt of arterial blood since the filtration fraction does not vary by comparison to sheep on regular diets. Thus, the reduction in renal plasma flow (PAH clearance), induced by low protein rations, is not dependent on any change in PAH extraction. This reduction is probably responsible for the simultaneous decrease of glomerular filtration.
在喂食低蛋白日粮的绵羊中，肾脏对对氨基马尿酸（PAH）和菊粉的摄取不受血浆尿素水平下降或肾脏血浆流量本身下降的影响。肾小球滤过率的显著降低并非由于动脉血在肾小球前分流，因为与正常日粮的绵羊相比，滤过分数没有变化。因此，低蛋白日粮引起的肾脏血浆流量（PAH清除率）降低并不依赖于PAH摄取的任何变化。这种降低可能是肾小球滤过同时下降的原因。
