Aleksandrova N Z, Minaev V I, Gorelov A V
Antibiot Khimioter. 1990 Mar;35(3):34-6.
Sensitivity of 179 strains of thermophilic Campylobacter to 21 chemotherapeutic drugs was studied. Activity of the antibacterial agents against the pathogens was estimated by the MICs. The MIC50 and MIC90 were also determined. All the Campylobacter strains were sensitive to gentamicin, chloramphenicol, neomycin, furazolidone and furagin and resistant to cefazolin, polymyxin E, rifampicin, vancomycin and bacitracin. Differences in the attitude of the Campylobacter isolates from various sources and patients of various age groups to the chemotherapeutic drugs were detected. Possible consideration of the results of comparison of R spectra of Campylobacter strains and the levels of their resistance to antimicrobial drugs as epidemiological markers is discussed.
研究了179株嗜热弯曲菌对21种化疗药物的敏感性。通过最低抑菌浓度（MICs）评估抗菌剂对病原体的活性。还测定了MIC50和MIC90。所有弯曲菌菌株对庆大霉素、氯霉素、新霉素、呋喃唑酮和硝呋拉净敏感，对头孢唑林、多粘菌素E、利福平、万古霉素和杆菌肽耐药。检测到来自不同来源和不同年龄组患者的弯曲菌分离株对化疗药物的反应存在差异。讨论了将弯曲菌菌株的R谱比较结果及其对抗菌药物的耐药水平作为流行病学标志物的可能性。
