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47种抗菌剂对来自猪的三种弯曲杆菌属细菌的体外活性

In vitro activities of 47 antimicrobial agents against three Campylobacter spp. from pigs.

作者信息

Gebhart C J, Ward G E, Kurtz H J

出版信息

Antimicrob Agents Chemother. 1985 Jan;27(1):55-9. doi: 10.1128/AAC.27.1.55.

DOI:10.1128/AAC.27.1.55
PMID:3985597
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC176204/
Abstract

The in vitro activities of 47 antimicrobial agents against 30 isolates of Campylobacter species from pigs were determined by the agar dilution technique. The isolates were obtained from pigs with proliferative enteritis and included 10 strains each of Campylobacter coli, Campylobacter sputorum subsp. mucosalis, and "Campylobacter hyointestinalis Gebhart et al." (this name is not on the Approved Lists). Carbadox, furazolidone, nitrofurantoin, gentamicin, and dimetridazole were the most active drugs, inhibiting all three Campylobacter species with a MIC for 50% of the isolates of 2 micrograms/ml or less. Trimethoprim-sulfamethoxazole, cefazolin, sulfachloropyridazine, novobiocin, vancomycin, sulfathiazole, cyclohexamide, bacitracin, p-arsanilic acid, and colistin were the least active, with MICs for 50% of the isolates ranging from 16 to greater than or equal to 128 micrograms/ml.

摘要

采用琼脂稀释法测定了47种抗菌药物对30株猪源弯曲杆菌的体外活性。这些菌株取自患有增生性肠炎的猪,包括10株结肠弯曲杆菌、10株黏膜螺旋体弯曲杆菌亚种以及10株“猪肠道弯曲杆菌格哈特等”(该名称不在《认可名录》上)。卡巴氧、呋喃唑酮、呋喃妥因、庆大霉素和二甲硝唑是活性最强的药物,对所有三种弯曲杆菌均有抑制作用,50%的菌株的最低抑菌浓度为2微克/毫升或更低。甲氧苄啶-磺胺甲恶唑、头孢唑林、磺胺氯哒嗪、新生霉素、万古霉素、磺胺噻唑、环己酰胺、杆菌肽、对氨基苯胂酸和黏菌素活性最低,50%的菌株的最低抑菌浓度为16至大于或等于128微克/毫升。

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