Department of Surgery, Seoul National University Hospital, Seoul 110-744, South Korea.
World J Gastroenterol. 2013 Apr 21;19(15):2437-40. doi: 10.3748/wjg.v19.i15.2437.
Inflammatory bowel disease (IBD) is regarded as one of the risk factors for colorectal cancer, and early detection of cancer in these patients may be difficult, especially in pediatric patients. Prognosis of pediatric colorectal cancer is known to be poor, because of delayed diagnosis and unfavorable differentiation. We report a case of a pediatric patient with a 10-year history of ulcerative colitis who was diagnosed with sigmoid colon cancer when he was 15 years old. He underwent proctocolectomy with ileal pouch anal anastomosis. Postoperative pathological examination of the tumor revealed adenocarcinoma. The pericolic tissue layer was infiltrated, but metastases were not found in either of the two lymph nodes. Children with a long history of predisposing factors such as IBD need particular attention to the possibility of colorectal cancer. Early diagnosis through regular screening with colonoscopy is one of the most important critical factors for a good prognosis.
炎症性肠病（IBD）被认为是结直肠癌的危险因素之一，这些患者的癌症早期检测可能较为困难，尤其是儿科患者。众所周知，儿科结直肠癌的预后较差，这是由于诊断延迟和分化不良所致。我们报告了一例患有溃疡性结肠炎 10 年病史的儿科患者，他在 15 岁时被诊断为乙状结肠癌。他接受了直肠结肠切除术和回肠袋肛管吻合术。肿瘤的术后病理检查显示为腺癌。肿瘤侵犯了结肠旁组织层，但在两个淋巴结中均未发现转移。患有 IBD 等长期潜在因素的儿童需要特别注意结直肠癌的可能性。通过结肠镜定期筛查进行早期诊断是获得良好预后的最重要关键因素之一。
