Sano Takeshi, Hamada Shinshichi, Haitani Takao, Nakashima Masakazu, Kajita Yoichiro, Shichiri Yasumasa
Department of Urology, Otsu Municipal Hospital, Otsu, Japan.
Korean J Urol. 2013 Apr;54(4):271-3. doi: 10.4111/kju.2013.54.4.271. Epub 2013 Apr 16.
A 66-year-old man with a history of multiple transurethral resections for recurrent bladder tumors, staged as Ta according to the International Union Against Cancer staging guidelines, presented with a complaint of dry cough. A round nodule with a diameter of 7.5 cm was detected in the lung by chest computed tomography, and a video-assisted thoracoscopic lobectomy was performed. Pulmonary metastasis of recurrent bladder cancer was diagnosed by immunohistochemistry staining for the urothelium-specific protein uroplakin Ia. Subsequently, 2 cycles of systemic chemotherapy were administered. Two and a half years after treatment, no recurrence of pulmonary lesions has been detected. A combination of complete resection of pulmonary lesions and systemic chemotherapy may result in a good prognosis for patients with non-muscle-invasive bladder cancer.
一名66岁男性,有因复发性膀胱肿瘤多次经尿道切除术史,根据国际抗癌联盟分期指南分期为Ta期,因干咳前来就诊。胸部计算机断层扫描在肺部发现一个直径7.5厘米的圆形结节,遂行电视辅助胸腔镜肺叶切除术。通过对尿路上皮特异性蛋白uroplakin Ia进行免疫组化染色,诊断为复发性膀胱癌肺转移。随后,给予2个周期的全身化疗。治疗两年半后,未检测到肺部病变复发。对于非肌层浸润性膀胱癌患者,肺病变的完全切除与全身化疗相结合可能会带来良好的预后。