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[腹膜肥大细胞在过敏性休克发生中的作用]

[The role of peritoneal mast cells in the development of anaphylactic shock].

作者信息

Bashmakov Iu K, Briuzgina T S

出版信息

Fiziol Zh (1978). 1990 Mar-Apr;36(2):31-4.

PMID:2361552
Abstract

An increase in the content of mast cells and macrophages in the bronchoalveolar lavage, liberation of arachidonic acid from the alveolar surfactant, formerly blocked by the caused deficiency of peritoneal mast cells have been observed under conditions of the experiment excluding the possibility of the allergen-specific hyperplasia of mastocytes in respiratory organs--anaphylactoid response of rats to the intrauterine introduction of the egg-white. A conclusion is drawn as to the possibility of interregional migration of mast cells whose regulating function with regards to the surfactant phospholipids is likely to be accomplished in cooperation with alveolar macrophages.

摘要

在排除呼吸道器官中肥大细胞因过敏原特异性增生(大鼠对子宫内注入蛋清的类过敏反应)可能性的实验条件下,观察到支气管肺泡灌洗中肥大细胞和巨噬细胞含量增加,肺泡表面活性物质中花生四烯酸从前因腹膜肥大细胞缺乏而受阻的释放。得出结论,肥大细胞可能存在区域间迁移,其对表面活性磷脂的调节功能可能与肺泡巨噬细胞协同完成。

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