MMWR Morb Mortal Wkly Rep. 2013 Apr 26;62(16):305-7.
Obliterative bronchiolitis, a rare, irreversible form of fixed obstructive lung disease, has been identified in workers exposed to flavoring chemicals while working in the microwave-popcorn and flavoring-manufacturing industries; the occupational risk to workers outside these industries is largely unknown. This report describes two cases of obliterative bronchiolitis identified in workers employed in a small coffee-processing facility. Both patients' illness was misdiagnosed before they received a diagnosis of work-related obliterative bronchiolitis, which had not been identified previously in the coffee-processing industry. These cases reinforce the need for exposure evaluation in all industries in which workers are exposed to flavoring chemicals. Additionally, a high index of suspicion is required when these potentially exposed workers have progressive shortness of breath. If obliterative bronchiolitis is suspected, immediate protection from further exposure is crucial to prevent further deterioration of lung function.
闭塞性细支气管炎,一种罕见的、不可逆的固定性阻塞性肺部疾病,已在从事爆米花和调味料生产行业的工人中接触调味化学品的工人中发现;在这些行业之外,工人的职业风险在很大程度上是未知的。本报告描述了在一家小型咖啡加工设施工作的两名工人患闭塞性细支气管炎的病例。两名患者的疾病在他们被诊断为与工作相关的闭塞性细支气管炎之前都被误诊了,而这种疾病以前在咖啡加工业中没有被发现过。这些病例再次强调了在所有暴露于调味化学品的行业中进行暴露评估的必要性。此外,当这些潜在暴露的工人出现进行性呼吸急促时,需要高度怀疑是否患有闭塞性细支气管炎。如果怀疑患有闭塞性细支气管炎,立即停止进一步接触至关重要,以防止肺功能进一步恶化。