Frost M L, Treadwell P
Department of Dermatology, Indiana University Medical Center, Indianapolis.
Int J Dermatol. 1990 Jun;29(5):375-6. doi: 10.1111/j.1365-4362.1990.tb04768.x.
A 58-year-old black man with leg ulcers of 43 years duration responded to pentoxifylline 400 mg tid in 8 months. The ability of pentoxifylline to increase erythrocyte flexibility and decrease blood viscosity was the basis for our use of this agent. Oral pentoxifylline may be a useful adjunct in healing sickle cell leg ulcers and preventing their recurrence.