Sperling N M, Lin P T, Lucente F E
Department of Otolaryngology-Head and Neck Surgery, New York Eye and Ear Infirmary, NY 10003.
Head Neck. 1990 Jul-Aug;12(4):337-41. doi: 10.1002/hed.2880120411.
Cystic enlargement of the parotid gland is a newly described manifestation of infection with human immunodeficiency virus (HIV). A review of 15 such patients with respect to clinical presentation, natural history, and management is presented. Follow-up ranges from 1 to 27 months, averaging 10 months. In 47% of the patients, parotid swelling was the chief complaint leading to the diagnosis of HIV infection. T-cell analysis revealed the tendency for this lesion to occur in the early stages of immunodeficiency when T-cell counts are high. Histologic examination revealed findings resembling benign lymphoepithelial lesion. It is felt that these lesions are a local manifestation of a systemic disease and treatment should be tailored with this in mind. Surgical excision may not be necessary. Fine-needle aspiration (FNA) was found to be useful diagnostically and therapeutically. Recognition of this entity is essential for the head and neck specialist in providing an early diagnosis of HIV infection.
腮腺囊肿性肿大是人类免疫缺陷病毒（HIV）感染新发现的一种表现形式。本文对15例此类患者的临床表现、自然病程及治疗进行了回顾。随访时间为1至27个月，平均10个月。47%的患者以腮腺肿大为主要症状，进而诊断出HIV感染。T细胞分析显示，当T细胞计数较高时，该病变倾向于在免疫缺陷的早期阶段出现。组织学检查发现类似良性淋巴上皮病变的表现。认为这些病变是一种全身性疾病的局部表现，治疗时应考虑到这一点。可能无需手术切除。细针穿刺抽吸活检（FNA）在诊断和治疗方面均被证明是有用的。对于头颈专科医生而言，识别这一实体对于早期诊断HIV感染至关重要。
