Karadağ Adil, Yanık Keramettin, Ünal Nevzat, Odabaşı Hakan, Hökelek Murat
Ondokuz Mayıs Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Samsun, Türkiye.
Turkiye Parazitol Derg. 2013;37(1):28-31. doi: 10.5152/tpd.2013.07.
Cystic echinococcosis (CE) is an important health problem common in our country. In this study, anti-Echinococcus granulosus IgG antibodies were investigated in the serum samples of 454 patients who attended the Ondokuz Mayıs University, Faculty of Medicine, Department of Parasitology between 2005 and 2011.
IHA (Fumouze, France) and ELISA (R-Biopharm, Germany) tests were performed at the same time.
While serum samples from 328 patients (72%) were negative with both tests, 81 samples (18%) were found to be positive with both tests. Forty (49%) cases were female, 41 (51%) cases were male who were positive by both tests. 25 (31%) positive cases were between 31 and 50 years old. While IHA was negative for 33 patients (7%) ELISA was positive for the same samples. In 2 patients (0.4%), both tests revealed low-positivity.
Using these two tests together for serologic detection of cystic echinococcosis could be recommended because of the high sensitivity and specificity ratios.
囊性棘球蚴病（CE）是我国常见的一个重要健康问题。在本研究中，对2005年至2011年间在翁多库兹迈伊大学医学院寄生虫学系就诊的454例患者的血清样本进行了抗细粒棘球绦虫IgG抗体检测。
同时进行间接血凝试验（IHA，法国Fumouze公司）和酶联免疫吸附测定（ELISA，德国R-Biopharm公司）。
328例患者（72%）的血清样本两种检测均为阴性，81例样本（18%）两种检测均为阳性。两种检测均为阳性的患者中，40例（49%）为女性，41例（51%）为男性。25例（31%）阳性病例年龄在31至50岁之间。33例患者（7%）的IHA检测为阴性，而相同样本的ELISA检测为阳性。2例患者（0.4%）两种检测均显示低阳性。
由于灵敏度和特异度较高，推荐联合使用这两种检测方法进行囊性棘球蚴病的血清学检测。
