[The possible connection of adenylic nucleotides to the rhythm of protein synthesis in hepatocytes in vitro].

Circahoral protein synthesis rhythms observed in hepatocytes in vitro differ in phase from the oscillations of intracellular amount of ATP. ATP added to culture medium interferes with the rhythms of protein synthesis and intracellular DNA content. Addition of ADP increases both the incorporation level of hepatocytes and ATP content. The data obtained has been discussed.