Mohamed Ahmad, Ryan Monique M
Children's Neuroscience Centre, Royal Children's Hospital, Melbourne, Australia.
Handb Clin Neurol. 2013;113:1481-3. doi: 10.1016/B978-0-444-59565-2.00017-4.
Critical illness polyneuropathy and critical illness myopathy are well recognized in adults, in whom they commonly cause generalized weakness and muscle wasting, with failure to wean from mechanical ventilation. There is significant clinical and neurophysiological overlap between the two conditions. Critical illness polyneuropathy and critical illness myopathy can cause significant morbidity in critically ill children, but they have only occasionally been reported in childhood, and little is known of their prevalence or clinical significance in this population. These conditions seem to be clinically and electrophysiologically similar in children and adults, but prospective studies of these entities are required to better characterize their frequency, natural history, and clinical significance in pediatric practice.
危重病性多发性神经病和危重病性肌病在成人中已得到充分认识，它们通常会导致全身无力和肌肉萎缩，伴有机械通气撤机失败。这两种情况在临床和神经生理学上有显著重叠。危重病性多发性神经病和危重病性肌病可在危重症儿童中导致显著的发病率，但在儿童期仅有偶尔的报道，对于它们在该人群中的患病率或临床意义知之甚少。这些情况在儿童和成人中似乎在临床和电生理方面相似，但需要对这些实体进行前瞻性研究，以更好地描述它们在儿科实践中的发生率、自然史和临床意义。
