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用于血管支架的可生物降解镁合金的超疏水表面研究。

Research on super-hydrophobic surface of biodegradable magnesium alloys used for vascular stents.

机构信息

Institute of Metal Research, Chinese Academy of Science, Shenyang 110016, China.

出版信息

Mater Sci Eng C Mater Biol Appl. 2013 Jul 1;33(5):2885-90. doi: 10.1016/j.msec.2013.03.017. Epub 2013 Mar 21.

Abstract

Micro-nanometer scale structure of nubby clusters overlay was constructed on the surface of an AZ31 magnesium alloy by a wet chemical method. The super-hydrophobicity was achieved with a water contact angle of 142° and a sliding angle of about 5°. The microstructure and composition of the super-hydrophobic surface were characterized by SEM and FTIR. Potentiodynamic polarization and electrochemical impedance spectroscopy were used to evaluate the corrosion behavior, and the hemocompatibility of the super-hydrophobic surface was investigated by means of hemolytic and platelet adhesion tests. Results showed that the super-hydrophobic treatment could improve the corrosion resistance of magnesium alloys in PBS and inhibit blood platelet adhesion on the surface, which implied excellent hemocompatibility with controlled degradation.

摘要

通过湿法化学方法在 AZ31 镁合金表面构建了具有纳米级凸起簇覆盖层的微纳结构。通过接触角为 142°和滑动角约 5°实现超疏水性。采用 SEM 和 FTIR 对超疏水表面的微观结构和组成进行了表征。采用动电位极化和电化学阻抗谱评估了腐蚀行为,通过溶血和血小板黏附试验研究了超疏水表面的血液相容性。结果表明,超疏水处理可以提高镁合金在 PBS 中的耐腐蚀性,并抑制表面血小板黏附,表明具有控制降解的优异血液相容性。

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